Publication Name	World Journal of Orthopedics
Manuscript ID	100107
Country	Taiwan

Received	2024-08-07 08:02
Peer-Review Started	2024-08-07 08:02
To Make the First Decision
Return for Revision	2024-09-18 00:14
Revised	2024-09-26 12:15
Second Decision	2024-10-22 02:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-22 13:56
Articles in Press	2024-10-22 13:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-10-25 06:44
Publish the Manuscript Online	2024-11-15 09:06

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Editorial
Article Title	Cardiotoxicity concerns in total joint arthroplasty
Manuscript Source	Invited Manuscript
All Author List	Chun-Han Cheng, Wen-Rui Hao and Tzu-Hurng Cheng
ORCID	Author(s) ORCID Number Tzu-Hurng Cheng http://orcid.org/0000-0002-9155-4169
Funding Agency and Grant Number
Corresponding Author	Tzu-Hurng Cheng, PhD, Professor, Department of Biochemistry, School of Medicine, College of Medicine, China Medical University, No. 91 Xueshi Road, North District, Taichung City 404328, Taiwan. thcheng@mail.cmu.edu.tw
Key Words	Cardiotoxicity; Joint arthroplasty; Metal ions; Cobalt; Cardiac function
Core Tip	This editorial discusses the findings of the study of Brennan et al on the cardiotoxic effects of elevated metal concentrations in patients receiving total joint arthroplasty. Increased cobalt and titanium levels are associated with substantial changes in the cardiac structure and function. Emphasizing the importance of monitoring metal ion levels, this editorial underscores that further research should be conducted to improve the understanding and management of cardiovascular risk associated with metal exposure in these patients.
Publish Date	2024-11-15 09:06
Citation	<p>Cheng CH, Hao WR, Cheng TH. Cardiotoxicity concerns in total joint arthroplasty. <i>World J Orthop</i> 2024; 15(11): 1007-1014</p>
URL	https://www.wjgnet.com/2218-5836/full/v15/i11/1007.htm
DOI	https://dx.doi.org/10.5312/wjo.v15.i11.1007

Full Article (PDF)	WJO-15-1007-with-cover.pdf
Manuscript File	100107_Auto_Edited_070221.docx
Answering Reviewers	100107-answering-reviewers.pdf
Audio Core Tip	100107-audio.mp3
Conflict-of-Interest Disclosure Form	100107-conflict-of-interest-statement.pdf
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Non-Native Speakers of English Editing Certificate	100107-non-native-speakers.pdf
Peer-review Report	100107-peer-reviews.pdf
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Scientific Editor Work List	100107-scientific-editor-work-list.pdf
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CrossCheck Report	100107-crosscheck-report.pdf