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Articles Published Processes
4/18/2025 8:22:08 AM | Browse: 31 | Download: 24
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Received |
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2024-08-14 02:10 |
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Peer-Review Started |
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2024-08-07 09:29 |
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To Make the First Decision |
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Return for Revision |
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2024-12-26 06:58 |
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Revised |
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2025-01-08 08:17 |
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Second Decision |
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2025-02-26 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-02-26 09:43 |
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Articles in Press |
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2025-02-26 09:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-04-07 08:44 |
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Publish the Manuscript Online |
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2025-04-18 08:22 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Increased reflux burden on pre-transplant reflux testing independently predicts significant pulmonary function decline after lung transplantation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Wai-Kit Lo, Annel M Fernandez, Natan Feldman, Nirmal Sharma, Hilary J Goldberg and Walter W Chan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Walter W Chan, AGAF, Associate Professor, FACG, MD, Department of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115, United States. wwchan@bwh.harvard.edu |
| Key Words |
Gastroesophageal reflux disease; Lung transplant; Multichannel intraluminal impedance; pH-monitoring; Bronchiolitis obliterans syndrome; Chronic rejection |
| Core Tip |
Gastroesophageal reflux has been associated with increased morbidity and mortality after lung transplantation. Abnormal objective measures of reflux on pre-transplant multichannel intraluminal impedance and pH have also been associated with early allograft injury, early rehospitalization and development of bronchiolitis obliterans syndrome and chronic lung allograft dysfunction. However, the relationship between pre-transplant reflux severity and pulmonary function decline after lung transplant remains unclear. Out study demonstrated that abnormal acid exposure time on pre-transplant reflux testing was associated with significant pulmonary function decline defined as ≥ 20% decrease in post-transplant baseline forced expiratory volume in one second. Patients with acid reflux and forced expiratory volume in one second decline are at high risk of poor lung transplant outcomes and should be aggressively managed. |
| Publish Date |
2025-04-18 08:22 |
| Citation |
<p>Lo WK, Fernandez AM, Feldman N, Sharma N, Goldberg HJ, Chan WW. Increased reflux burden on pre-transplant reflux testing independently predicts significant pulmonary function decline after lung transplantation. <i>World J Transplant</i> 2025; 15(3): 100111</p> |
| URL |
https://www.wjgnet.com/2220-3230/full/v15/i3/100111.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v15.i3.100111 |
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