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Articles Published Processes
2/14/2025 10:33:16 AM | Browse: 187 | Download: 708
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Received |
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2024-08-11 14:45 |
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Peer-Review Started |
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2024-08-11 14:45 |
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First Decision by Editorial Office Director |
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2024-10-20 11:03 |
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Return for Revision |
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2024-10-20 11:03 |
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Revised |
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2024-11-03 05:48 |
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Publication Fee Transferred |
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2024-11-09 01:21 |
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Second Decision by Editor |
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2024-12-13 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-12-13 06:25 |
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Articles in Press |
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2024-12-13 06:25 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-01-22 03:43 |
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Publish the Manuscript Online |
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2025-02-14 10:33 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Report |
| Article Title |
Penile metastasis from colon cancer with BRAFV600E mutation treated with BRAF/MEK-targeted therapy plus cetuximab: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun-Chen Wu, Hua-Xi Cheng, Qiu-Sheng Lan, He-Yang Xu, Yu-Jie Zeng, Wei Lai and Zhong-Hua Chu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81871981 |
| Natural Science Foundation of Guangdong Province |
2022A1515012348 and 2023A1515010457 |
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| Corresponding Author |
Zhong-Hua Chu, MD, PhD, Professor, Department of Gastrointestinal Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yan Jiang West Road, Guangzhou 510120, Guangdong Province, China. chuzhh@mail.sysu.edu.cn |
| Key Words |
Colon cancer; Penile metastasis; BRAFV600E mutation; Targeted therapy; Case report |
| Core Tip |
Despite the increasing incidence and prevalence of colorectal cancer among malignant tumors, penile metastasis originating from colorectal cancer remains a rare occurrence. The precise mechanism underlying penile metastasis of colorectal cancer remains elusive, and its specific treatment remains a subject of controversy, particularly in patients with BRAFV600E mutation, which often signifies an unfavorable prognosis. In our case, the treatment of BRAF/MEK-targeted therapy (dabrafenib and trametinib) plus cetuximab demonstrated promising outcomes, leading to tumor regression and prolonged survival, thereby offering valuable insights for the management of analogous cases. |
| Publish Date |
2025-02-14 10:33 |
| Citation |
Wu JC, Cheng HX, Lan QS, Xu HY, Zeng YJ, Lai W, Chu ZH. Penile metastasis from colon cancer with BRAFV600E mutation treated with BRAF/MEK-targeted therapy plus cetuximab: A case report. World J Gastrointest Oncol 2025; 17(3): 100152 |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i3/100152.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i3.100152 |
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