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2/21/2025 10:13:09 AM | Browse: 28 | Download: 66
Publication Name World Journal of Transplantation
Manuscript ID 100157
Country Italy
Received
2024-08-14 02:10
Peer-Review Started
2024-08-08 10:50
To Make the First Decision
Return for Revision
2024-12-11 06:54
Revised
2024-12-20 12:06
Second Decision
2025-01-21 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-01-21 07:33
Articles in Press
2025-01-21 07:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-02-08 04:07
Publish the Manuscript Online
2025-02-21 10:13
ISSN 2220-3230 (online)
Open Access Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Retrospective Study
Article Title Significance of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio as prognostic predictors after liver transplantation
Manuscript Source Invited Manuscript
All Author List Marco Maria Pascale, Francesco Frongillo, Pierangelo Vasta, Giuseppe Massimiani, Erida Nure and Salvatore Agnes
ORCID
Author(s) ORCID Number
Marco Maria Pascale http://orcid.org/0000-0003-1355-0207
Salvatore Agnes http://orcid.org/0000-0002-3374-4060
Funding Agency and Grant Number
Corresponding Author Marco Maria Pascale, MD, General Surgery and Liver Transplantation Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 8 largo A Gemelli, Rome 00168, Italy. marcomaria.pascale@policlinicogemelli.it
Key Words Liver transplantation; Immunobiomarkers; Neutrophil-to-lymphocyte ratio; Neutrophil-to-platelet ratio; Post-operative complications
Core Tip The neutrophil-to-lymphocyte ratio (NLR) and neutrophil-to-platelet ratio (NPR) are emerging biomarkers used to predict early outcomes following liver transplantation. Elevated NLR indicates systemic inflammation, which can signal complications like infection or rejection. High NPR values can reflect underlying inflammation and potential vascular complications. Both ratios are calculated from routine blood tests, making them cost-effective and readily available. Studies suggest that higher pre-transplant NLR and NPR levels are associated with increased risk of poor graft function, longer hospital stays, and mortality. Monitoring these ratios helps in identifying at-risk patients, guiding post-operative care, and improving overall transplant success.
Publish Date 2025-02-21 10:13
Citation <p>Pascale MM, Frongillo F, Vasta P, Massimiani G, Nure E, Agnes S. Significance of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio as prognostic predictors after liver transplantation. <i>World J Transplant</i> 2025; 15(2): 100157</p>
URL https://www.wjgnet.com/2220-3230/full/v15/i2/100157.htm
DOI https://dx.doi.org/10.5500/wjt.v15.i2.100157
Full Article (PDF) WJT-15-100157-with-cover.pdf
Manuscript File 100157_Auto_Edited_141329.docx
Answering Reviewers 100157-answering-reviewers.pdf
Audio Core Tip 100157-audio.m4a
Biostatistics Review Certificate 100157-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 100157-conflict-of-interest-statement.pdf
Copyright License Agreement 100157-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 100157-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 100157-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 100157-non-native-speakers.pdf
Peer-review Report 100157-peer-reviews.pdf
Scientific Misconduct Check 100157-scientific-misconduct-check.png
Scientific Editor Work List 100157-scientific-editor-work-list.pdf
CrossCheck Report 100157-crosscheck-report.pdf