| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Prognostic impact and reasons for variability by tumor location in gastric cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Xing Huang, Han-Yi He, Ken Chen, Hai-Dong Liu, Dan Zu, Chen Liang, Qi-Mei Bao, Yang-Chan Hu, Guo-Xia Liu, Yu-Ke Zhong, Chun-Kai Zhang, Ming-Cong Deng, Yan-Hua He, Ji Jing, Yin Shi, Sheng-Feng Xu, Yao-Shu Teng, Zu Ye and Xiang-Dong Cheng |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 82473195 |
| Natural Science Foundation of Zhejiang Province |
No. LTGY23H160018 |
| Zhejiang Medical and Health Science and Technology Program |
No. 2024KY789 |
| Beijing Science and Technology Innovation Medical Development Foundation |
No. KC2023-JX-0270-07 |
| National Natural Science Foundation of China |
No. 32370797 |
|
| Corresponding Author |
Xiang-Dong Cheng, MD, Professor, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, No. 1 East Banshan Road, Hangzhou 310022, Zhejiang Province, China. yezuqscx@gmail.com |
| Key Words |
Gastric cancer; Clinicopathologic characteristics; Tumor marker; Tumor location; Overall survival |
| Core Tip |
This study investigates how the location of gastric cancer (GC) impacts prognosis by analyzing data from 3287 patients who underwent gastrectomy. It reveals that clinicopathological factors, including gender, age, and serum levels of carcinoembryonic antigen, carbohydrate antigen (CA) 19-9, and CA72-4, significantly influence tumor location. Notably, GC located in the “lower” and “middle” regions correlates with a better overall survival compared to other locations. These findings underscore the importance of tumor location in predicting patient outcomes and guiding postoperative management strategies. |
| Publish Date |
2024-11-12 06:08 |
| Citation |
<p>Huang YX, He HY, Chen K, Liu HD, Zu D, Liang C, Bao QM, Hu YC, Liu GX, Zhong YK, Zhang CK, Deng MC, He YH, Jing J, Shi Y, Xu SF, Teng YS, Ye Z, Cheng XD. Prognostic impact and reasons for variability by tumor location in gastric cancer. <i>World J Gastroenterol</i> 2024; 30(44): 4709-4724</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i44/4709.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i44.4709 |
