Publication Name	World Journal of Psychiatry
Manuscript ID	100214
Country	China

Received	2024-08-10 01:54
Peer-Review Started	2024-08-10 01:54
To Make the First Decision
Return for Revision	2024-11-25 10:47
Revised	2024-11-26 16:11
Second Decision	2024-12-17 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-17 08:57
Articles in Press	2024-12-17 08:57
Publication Fee Transferred	2024-11-27 01:53
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-01-01 02:27
Publish the Manuscript Online	2025-01-14 08:49

ISSN	2220-3206 (online)
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Category	Psychiatry
Manuscript Type	Basic Study
Article Title	Integrative transcriptomic and proteomic analysis reveals that SERPING1 inhibits neuronal proliferation via the CaMKII-CREB-BDNF pathway in schizophrenia
Manuscript Source	Unsolicited Manuscript
All Author List	Feng Li, Xing Ren, Jia-Xiu Liu, Tian-Dao Wang, Bi Wang and Xiao-Bin Wei
ORCID	Author(s) ORCID Number Feng Li http://orcid.org/0000-0003-3771-3816 Xiao-Bin Wei http://orcid.org/0000-0002-9386-7556
Funding Agency and Grant Number	Funding Agency Grant Number Key R&D Projects of Hainan Province ZDYF2022SHFZ295
Corresponding Author	Xiao-Bin Wei, MD, Professor, Department of Clinical Laboratory, The Affiliated Haikou Hospital of Xiangya Medical College, Central South University, No. 43 Renmin Avenue, Meilan District, Haikou 570208, Hainan Province, China. weixb1972@163.com
Key Words	Transcriptomics; Proteomics; Schizophrenia; SERPING1; Pathogenesis
Core Tip	The strength of this study lies in the integration of transcriptomics and proteomics data from the same sample source (peripheral blood mononuclear cells) to better observe mRNA-protein inconsistencies and mRNA-protein correlations, thus explaining the biology of schizophrenia in a holistic manner. Proteomics and transcriptomics correlation analyses provide a panoramic view of the expression profile of schizophrenia, enabling complementarity and integration at the transcriptional and protein levels. Again, this study is one of the few to investigate the role of the SERPING1 gene in neural cell proliferation and apoptosis.
Publish Date	2025-01-14 08:49
Citation	<p>Li F, Ren X, Liu JX, Wang TD, Wang B, Wei XB. Integrative transcriptomic and proteomic analysis reveals that SERPING1 inhibits neuronal proliferation via the CaMKII-CREB-BDNF pathway in schizophrenia. <i>World J Psychiatry</i> 2025; 15(2): 100214</p>
URL	https://www.wjgnet.com/2220-3206/full/v15/i2/100214.htm
DOI	https://dx.doi.org/10.5498/wjp.v15.i2.100214

Full Article (PDF)	WJP-15-100214-with-cover.pdf
Manuscript File	100214_Auto_Edited_082846.docx
Answering Reviewers	100214-answering-reviewers.pdf
Audio Core Tip	100214-audio.mp3
Biostatistics Review Certificate	100214-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	100214-conflict-of-interest-statement.pdf
Copyright License Agreement	100214-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	100214-foundation-statement.pdf
Institutional Review Board Approval Form or Document	100214-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	100214-non-native-speakers.pdf
Supplementary Material	100214-supplementary-material.pdf
Peer-review Report	100214-peer-reviews.pdf
Scientific Misconduct Check	100214-scientific-misconduct-check.png
Scientific Editor Work List	100214-scientific-editor-work-list.pdf
CrossCheck Report	100214-crosscheck-report.pdf