| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Case Control Study |
| Article Title |
Degree centrality values in the left calcarine as a potential imaging biomarker for anxious major depressive disorder
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu-Jun Gao, Li-Li Meng, Zhao-Yuan Lu, Xiang-You Li, Ru-Qin Luo, Hang Lin, Zhi-Ming Pan, Bao-Hua Xu, Qian-Kun Huang, Zhi-Gang Xiao, Ting-Ting Li, E Yin, Nian Wei, Chen Liu and Hong Lin |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Hubei Provincial Department of Science and Technology Natural Fund |
2024AFC0S6 |
| the Open Fund of the Mental Health Research Institute at Three Gorges University |
YCXL-23-11 |
|
| Corresponding Author |
Yu-Jun Gao, PhD, Department of Psychiatry, Wuhan Wuchang Hospital, No. 505 South Luoshi Road, Hongshan District, Wuhan 430064, Hubei Province, China. gaoyujun19820214@163.com |
| Key Words |
Major depressive disorder; Anxiety; Degree centrality; Resting-state functional magnetic resonance imaging |
| Core Tip |
In this study, we investigated brain regions with altered degree centrality (DC) values by detecting DC in anxious major depressive disorder (MDD) patients and non-anxious MDD patients, and characterized them as possible neuroimaging biomarkers using receiver operator characteristic analysis. The results of our study showed that DC values of the right fusiform gyrus and bilateral calcarine (CAL) were reduced in the anxious MDD group compared to the non-anxious MDD group. Abnormal DC values in the left CAL may distinguish MDD from its anxiety subtype and serve as a potential neuroimaging biomarker for anxious MDD. |
| Publish Date |
2025-03-25 10:06 |
| Citation |
<p>Gao YJ, Meng LL, Lu ZY, XYL, Luo RQ, Lin H, Pan ZM, Xu BH, Huang QK, Xiao ZG, Li TT, Yin E, Wei N, Liu C, Lin H. Degree centrality values in the left calcarine as a potential imaging biomarker for anxious major depressive disorder. <i>World J Psychiatry</i> 2025; 15(4): 100289</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i4/100289.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i4.100289 |
