Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	100292
Country	China

Received	2024-08-13 09:09
Peer-Review Started	2024-08-13 09:09
To Make the First Decision
Return for Revision	2024-11-15 07:46
Revised	2024-11-26 15:57
Second Decision	2024-12-17 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-17 08:13
Articles in Press	2024-12-17 08:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-01-22 03:47
Publish the Manuscript Online	2025-02-14 10:33

ISSN	1948-5204 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Potential role of coagulation markers in early detection of bone metastasis in gastric cancer: A critical review
Manuscript Source	Unsolicited Manuscript
All Author List	Qing-Nan Lin, Qian Wu, Chong Lv, Jun Tang, Ling-Yun Zhao and Ke-Yang Xu
ORCID	Author(s) ORCID Number Ling-Yun Zhao http://orcid.org/0000-0002-7055-2746 Ke-Yang Xu http://orcid.org/0000-0002-7049-2528
Funding Agency and Grant Number
Corresponding Author	Ke-Yang Xu, Assistant Professor, MD, PhD, Faculty of Chinese Medicine, and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida WaiLong, Taipa, Macau, Macau 999078, China. 21482055@life.hkbu.edu.hk
Key Words	Gastric cancer; Bone metastasis; Coagulation markers; Prothrombin time; Activated partial thromboplastin time; Fibrin degradation products; Diagnostic indicators; Oncology
Core Tip	This letter aims to highlight the potential of tests for coagulation markers as cost-effective, non-invasive tools for early detection of bone metastasis in gastric cancer patients. To enhance the study's applicability, it is crucial to clarify patient grouping criteria and imaging methodologies. Additionally, incorporating diverse, multi-center cohorts and exploring a broader range of biomarkers may strengthen the findings of previous studies. Future research should also consider the impact of treatment on biomarker levels and the underlying mechanisms of hypercoagulability in metastasis to improve patients’ outcomes.
Publish Date	2025-02-14 10:33
Citation	<p>Lin QN, Wu Q, Lv C, Tang J, Zhao LY, Xu KY. Potential role of coagulation markers in early detection of bone metastasis in gastric cancer: A critical review. <i>World J Gastrointest Oncol</i> 2025; 17(3): 100292</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i3/100292.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i3.100292

Full Article (PDF)	WJGO-17-100292-with-cover.pdf
Manuscript File	100292_Auto_Edited_082314.docx
Answering Reviewers	100292-answering-reviewers.pdf
Audio Core Tip	100292-audio.m4a
Conflict-of-Interest Disclosure Form	100292-conflict-of-interest-statement.pdf
Copyright License Agreement	100292-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	100292-non-native-speakers.pdf
Peer-review Report	100292-peer-reviews.pdf
Scientific Misconduct Check	100292-scientific-misconduct-check.png
Scientific Editor Work List	100292-scientific-editor-work-list.pdf
CrossCheck Report	100292-crosscheck-report.pdf