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Articles Published Processes
12/18/2024 8:36:40 AM | Browse: 146 | Download: 503
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Received |
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2024-08-12 23:10 |
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Peer-Review Started |
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2024-08-12 23:10 |
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First Decision by Editorial Office Director |
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2024-10-23 10:50 |
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Return for Revision |
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2024-10-23 10:50 |
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Revised |
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2024-10-31 21:20 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-11-21 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-11-21 07:59 |
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Articles in Press |
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2024-11-21 07:59 |
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Edit the Manuscript by Language Editor |
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2024-11-24 12:16 |
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Typeset the Manuscript |
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2024-12-02 02:32 |
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Publish the Manuscript Online |
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2024-12-18 08:36 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychology, Clinical |
| Manuscript Type |
Editorial |
| Article Title |
Interleukin-6 in epilepsy and its neuropsychiatric comorbidities: How to bridge the gap
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Xiao-Man Chen, Shuo Zhang, Shi-Qi Gao and Michael Xu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Shuo Zhang, Assistant Professor, MD, PhD, Department of Neurology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang 110004, Liaoning Province, China. flybird31025@163.com |
| Key Words |
Epilepsy; Interleukin-6; Neuropsychiatric comorbidities; Depression; Tocilizumab; Neuroinflammation; Interleukin-6 receptor blockade |
| Core Tip |
Interleukin (IL)-6 homeostasis is crucial to the pathophysiology of epilepsy and its associated neuropsychiatric comorbidities, suggesting its potential utility as a biomarker for disease activity. Therapeutic strategies aimed at inhibiting IL-6 signaling through receptor blockade represent a novel and promising approach for treating epilepsy and its neuropsychiatric manifestations. Elucidating the mechanisms by which IL-6 modulates epilepsy and its neuropsychiatric comorbidities can provide valuable insights into potential therapeutic targets, thereby enhancing patient outcomes. |
| Publish Date |
2024-12-18 08:36 |
| Citation |
Chen XM, Zhang S, Gao SQ, Xu M. Interleukin-6 in epilepsy and its neuropsychiatric comorbidities: How to bridge the gap. World J Psychiatry 2025; 15(1): 100297 |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i1/100297.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i1.100297 |
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