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Articles Published Processes
10/24/2024 9:16:56 AM | Browse: 49 | Download: 196
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Received |
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2024-08-15 08:02 |
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Peer-Review Started |
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2024-08-15 08:02 |
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To Make the First Decision |
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Return for Revision |
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2024-09-01 16:16 |
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Revised |
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2024-09-04 08:59 |
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Second Decision |
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2024-09-24 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-09-25 11:57 |
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Articles in Press |
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2024-09-25 11:57 |
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Publication Fee Transferred |
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2024-09-27 09:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-10-16 04:17 |
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Publish the Manuscript Online |
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2024-10-24 09:16 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Gut microbiota changes associated with frailty in older adults: A systematic review of observational studies
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Na-Na Wen, Li-Wei Sun, Qian Geng and Guo-Hua Zheng |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Guo-Hua Zheng, PhD, Professor, College of Nursing and Health Management, Shanghai University of Medicine and Health Sciences, No. 279 Zhouzhu Road, Pudong New District, Shanghai 201318, China. zhenggh@sumhs.edu.cn |
| Key Words |
Frailty; Gut microbiota; Observational study; Older adults; Systematic review |
| Core Tip |
A growing number of studies have reported changes in the composition and diversity of the gut microbiota between frail and healthy older adults, suggesting that alterations in the gut microbiota may play a key role in the pathophysiology of frailty; however, direct assessment of the associations between changes in the gut microbiome and frailty in older adults remains limited. This review revealed a significant decrease in α diversity and a significant increase in β diversity in frail older adults compared with non-frail older adults, which was commonly reflected by a reduction in beneficial species and an increase in pathogenic species. This study provides a comprehensive overview of the relationship between changes in the gut microbiota and frailty in older adults and suggests a possible role for the gut microbiota in the pathogenesis of frailty. |
| Publish Date |
2024-10-24 09:16 |
| Citation |
<p>Wen NN, Sun LW, Geng Q, Zheng GH. Gut microbiota changes associated with frailty in older adults: A systematic review of observational studies. <i>World J Clin Cases</i> 2024; 12(35): 6815-6825</p> |
| URL |
https://www.wjgnet.com/2307-8960/full/v12/i35/6815.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v12.i35.6815 |
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