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2/28/2025 10:46:30 AM | Browse: 70 | Download: 76
Publication Name World Journal of Diabetes
Manuscript ID 100467
Country Saudi Arabia
Received
2024-08-19 03:19
Peer-Review Started
2024-08-21 00:29
To Make the First Decision
Return for Revision
2024-12-26 07:15
Revised
2025-01-06 09:43
Second Decision
2025-01-17 02:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-01-17 05:47
Articles in Press
2025-01-17 05:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
2025-01-23 12:38
Typeset the Manuscript
2025-02-05 11:35
Publish the Manuscript Online
2025-02-28 10:46
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Letter to the Editor
Article Title Platelets indices clinical implications in diabetes mellitus: A broader insight
Manuscript Source Invited Manuscript
All Author List Hyder Osman Mirghani
ORCID
Author(s) ORCID Number
Hyder Osman Mirghani http://orcid.org/0000-0002-5817-6194
Funding Agency and Grant Number
Corresponding Author Hyder Osman Mirghani, MD, Professor, Internal Medicine, University of Tabuk, Prince Fahd Bin Sulta, Tabuk 51941, Saudi Arabia. s.hyder63@hotmail.com
Key Words Platelets indices; Mean platelets volume; Glucoregulation; Cardiovascular risk
Core Tip Mean platelet volume (MPV), plateletcrit (PLC), and platelet distribution width (PLDW) have been touched on in the literature as parameters of glucoregulation. However, their clinical implications in real-world diabetes care are blurry and unclear. Platelet indices (PIs) if estimated within two hours of blood collection could be useful indicators of glycemic control in type 1 and type 2 diabetes in low-income countries, and reflect the glycemic status in the previous two weeks (the platelet lifespan). Importantly, PIs are not specific and are affected by demographic factors, renal failure, pregnancy, malignancies, and infection. Therefore, combination with blood glucose measurement and the development of local cut-off levels are crucial. PIs have the advantage of reflecting the previous two weeks' glycemic control compared to the HbA1c which reflects glycemic control during the red blood cells' lifespan (120 days). Because of the above, PIs could be useful before surgery, and during pregnancy (with pregnancy cut-off). MPV, and PLC, are more affected by confounders, and because of that PLDW is more specific.
Publish Date 2025-02-28 10:46
Citation <p>Mirghani HO. Platelets indices clinical implications in diabetes mellitus: A broader insight. <i>World J Diabetes</i> 2025; 16(4): 100467</p>
URL https://www.wjgnet.com/1948-9358/full/v16/i4/100467.htm
DOI https://dx.doi.org/10.4239/wjd.v16.i4.100467
Full Article (PDF) WJD-16-100467-with-cover.pdf
Manuscript File 100467_Auto_Edited_035940.docx
Answering Reviewers 100467-answering-reviewers.pdf
Audio Core Tip 100467-audio.m4a
Conflict-of-Interest Disclosure Form 100467-conflict-of-interest-statement.pdf
Copyright License Agreement 100467-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 100467-non-native-speakers.pdf
Peer-review Report 100467-peer-reviews.pdf
Scientific Misconduct Check 100467-scientific-misconduct-check.png
Scientific Editor Work List 100467-scientific-editor-work-list.pdf
CrossCheck Report 100467-crosscheck-report.pdf