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Articles Published Processes
1/18/2025 8:12:01 AM | Browse: 42 | Download: 99
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Received |
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2024-08-19 12:00 |
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Peer-Review Started |
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2024-08-19 12:00 |
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To Make the First Decision |
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Return for Revision |
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2024-10-23 01:42 |
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Revised |
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2024-11-02 18:19 |
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Second Decision |
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2024-11-20 02:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-11-20 08:11 |
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Articles in Press |
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2024-11-20 08:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-11-24 01:47 |
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Publish the Manuscript Online |
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2025-01-18 08:12 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Editorial |
| Article Title |
Protein tyrosine phosphatase nonreceptor 2: A New biomarker for digestive tract cancers
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ozlem Ceren Gunizi and Gulsum Ozlem Elpek |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Gulsum Ozlem Elpek, MD, Professor, Department of Pathology, Akdeniz University Medical School, Dumlupinar Bulvarı, Antalya 07070, Türkiye. elpek@akdeniz.edu.tr |
| Key Words |
Protein tyrosine phosphatase nonreceptor 2; Digestive tract cancers; Gastrointestinal cancer; Biomarker |
| Core Tip |
Protein tyrosine phosphatase nonreceptor 2 (PTPN2) is a member of the protein tyrosine phosphatase family of signaling proteins. Numerous studies have examined the roles of this molecule in antitumor immunity and therapy because of its significant effects on a wide range of events, including the production and distribution of immune cells and numerous pathways that are important to the behavior and treatment of cancers. The role of PTPN2 in gastrointestinal (GI) cancers has been investigated in a limited number of studies, indicating that PTPN2 has heterogeneous effects on different tumors and even on the same type of GI cancer. Currently, this situation limits the recommendation of PTPN2 as a potential biomarker for predicting cancer prognosis and the efficacy of immunotherapy necessitates further studies in GI tumors. |
| Publish Date |
2025-01-18 08:12 |
| Citation |
<p>Gunizi OC, Elpek GO. Protein tyrosine phosphatase nonreceptor 2: A New biomarker for digestive tract cancers. <i>World J Gastrointest Oncol</i> 2025; 17(2): 100546</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i2/100546.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i2.100546 |
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