Publication Name	World Journal of Clinical Oncology
Manuscript ID	100695
Country	Japan

Received	2024-08-23 10:23
Peer-Review Started	2024-08-23 10:23
To Make the First Decision
Return for Revision	2024-09-17 02:47
Revised	2024-09-19 05:43
Second Decision	2024-09-27 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-27 11:22
Articles in Press	2024-09-27 11:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-10-09 05:50
Publish the Manuscript Online	2024-10-14 07:12

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Editorial
Article Title	Radical radiotherapy without surgical tumor resection for rectal cancer
Manuscript Source	Invited Manuscript
All Author List	Takashi Ono and Masashi Koto
ORCID	Author(s) ORCID Number Takashi Ono http://orcid.org/0000-0002-9711-1158
Funding Agency and Grant Number
Corresponding Author	Takashi Ono, MD, PhD, Assistant Professor, Doctor, Doctor, Department of Radiation Oncology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. abc1123513@gmail.com
Key Words	Rectal cancer; Locally recurrent rectal cancer; Total neoadjuvant therapy; Watch-and-wait; Carbon ion radiotherapy; Proton beam therapy
Core Tip	This editorial focuses on non-surgical radical treatments for rectal cancer. Total neoadjuvant therapy has demonstrated a high complete response. This success has made the watch-and-wait strategy a viable option for some patients. However, establishing standardized follow-up methods is essential. Carbon ion radiotherapy has demonstrated high local control with a low incidence of severe late toxicities, even after previous pelvic radiotherapy. While these new non-surgical curative treatments for rectal cancer require further investigation, future advancements in this field are anticipated.
Publish Date	2024-10-14 07:12
Citation	<p>Ono T, Koto M. Radical radiotherapy without surgical tumor resection for rectal cancer. <i>World J Clin Oncol</i> 2024; 15(11): 1390-1393</p>
URL	https://www.wjgnet.com/2218-4333/full/v15/i11/1390.htm
DOI	https://dx.doi.org/10.5306/wjco.v15.i11.1390

Full Article (PDF)	WJCO-15-1390-with-cover.pdf
Manuscript File	100695_Auto_Edited_134648.docx
Answering Reviewers	100695-answering-reviewers.pdf
Audio Core Tip	100695-audio.mp3
Conflict-of-Interest Disclosure Form	100695-conflict-of-interest-statement.pdf
Copyright License Agreement	100695-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	100695-non-native-speakers.pdf
Peer-review Report	100695-peer-reviews.pdf
Scientific Misconduct Check	100695-scientific-misconduct-check.png
Scientific Editor Work List	100695-scientific-editor-work-list.pdf
CrossCheck Report	100695-crosscheck-report.pdf