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Articles Published Processes
1/18/2015 4:09:00 PM | Browse: 1098 | Download: 1393
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Received |
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2014-03-11 21:20 |
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Peer-Review Started |
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2014-03-12 09:53 |
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To Make the First Decision |
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2014-04-02 19:34 |
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Return for Revision |
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2014-04-14 08:09 |
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Revised |
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2014-05-10 14:00 |
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Second Decision |
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2014-07-22 16:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-07-22 18:21 |
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Articles in Press |
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2014-07-22 18:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-08-27 23:54 |
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Typeset the Manuscript |
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2014-12-29 09:46 |
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Publish the Manuscript Online |
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2015-01-18 16:09 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Copy number variations are progressively associated with the pathogenesis of colorectal cancer in ulcerative colitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bhadravathi Marigowda Shivakumar, Harish Rotti, Thanvanthri Gururajan Vasudevan, Aswath Balakrishnan, Sanjiban Chakrabarty, Ganesh Bhat, Lakshmi Rao, Cannanore Ganesh Pai and Kapaettu Satyamoorthy |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Department of Biotechnology |
BT/01/COE/06/02/07 |
| TIFAC-CORE in Pharmacogenomics, Government of India |
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| Corresponding Author |
Cannanore Ganesh Pai, Professor, Head, Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka 576104, India. cgpai@yahoo.co.in |
| Key Words |
Ulcerative colitis; Colorectal cancer; Molecular analysis; Microsatellite instability; Copy number variations |
| Core Tip |
Ulcerative colitis (UC) confers an increased risk of colorectal cancer (CRC). The role of copy number variations (CNVs) in different cancers including sporadic CRC has been established but their association in the development of colitis-associated neoplasia is not well described. Reports to date are limited to only a particular stage (e.g., dysplasia or cancer) in the development of colitis-associated cancer. In this first study of its kind, we report the association of increased numbers of known CNVs with the progression of UC to colitis-associated cancer. |
| Publish Date |
2015-01-18 16:09 |
| Citation |
Shivakumar BM, Rotti H, Vasudevan TG, Balakrishnan A, Chakrabarty S, Bhat G, Rao L, Pai CG, Satyamoorthy K. Copy number variations are progressively associated with the pathogenesis of colorectal cancer in ulcerative colitis. World J Gastroenterol 2015; 21(2): 616-622 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i2/616.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i2.616 |
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