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1/18/2015 4:09:00 PM | Browse: 582 | Download: 627
Publication Name World Journal of Gastroenterology
Manuscript ID 10070
Country/Territory India
Received
2014-03-11 21:20
Peer-Review Started
2014-03-12 09:53
To Make the First Decision
2014-04-02 19:34
Return for Revision
2014-04-14 08:09
Revised
2014-05-10 14:00
Second Decision
2014-07-22 16:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-07-22 18:21
Articles in Press
2014-07-22 18:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-08-27 23:54
Typeset the Manuscript
2014-12-29 09:46
Publish the Manuscript Online
2015-01-18 16:09
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Clinical Trials Study
Article Title Copy number variations are progressively associated with the pathogenesis of colorectal cancer in ulcerative colitis
Manuscript Source Unsolicited Manuscript
All Author List Bhadravathi Marigowda Shivakumar, Harish Rotti, Thanvanthri Gururajan Vasudevan, Aswath Balakrishnan, Sanjiban Chakrabarty, Ganesh Bhat, Lakshmi Rao, Cannanore Ganesh Pai and Kapaettu Satyamoorthy
Funding Agency and Grant Number
Funding Agency Grant Number
Department of Biotechnology BT/01/COE/06/02/07
TIFAC-CORE in Pharmacogenomics, Government of India
Corresponding author Cannanore Ganesh Pai, Professor, Head, Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka 576104, India. cgpai@yahoo.co.in
Keywords Ulcerative colitis; Colorectal cancer; Molecular analysis; Microsatellite instability; Copy number variations
Core Tip Ulcerative colitis (UC) confers an increased risk of colorectal cancer (CRC). The role of copy number variations (CNVs) in different cancers including sporadic CRC has been established but their association in the development of colitis-associated neoplasia is not well described. Reports to date are limited to only a particular stage (e.g., dysplasia or cancer) in the development of colitis-associated cancer. In this first study of its kind, we report the association of increased numbers of known CNVs with the progression of UC to colitis-associated cancer.
Publish Date 2015-01-18 16:09
Citation Shivakumar BM, Rotti H, Vasudevan TG, Balakrishnan A, Chakrabarty S, Bhat G, Rao L, Pai CG, Satyamoorthy K. Copy number variations are progressively associated with the pathogenesis of colorectal cancer in ulcerative colitis. World J Gastroenterol 2015; 21(2): 616-622
Url http://www.wjgnet.com/1007-9327/full/v21/i2/616.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i2.616
Full Article (PDF) WJG-21-616.pdf
Full Article (Word) WJG-21-616.doc
Manuscript File 10070-Review.doc
Answering Reviewers 10070-Answering reviewers.pdf
Copyright License Agreement 10070-Copyright assignment.pdf
Peer-review Report 10070-Peer review.pdf
Scientific Misconduct Check 10070-Crosscheck.JPG
Scientific Editor Work List 10070-Scientific editor work list.pdf