| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Azathioprine is essential following cyclosporine for patients with steroid-refractory ulcerative colitis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Nobuyuki Miyake, Takafumi Ando, Kazuhiro Ishiguro, Osamu Maeda, Osamu Watanabe, Yutaka Hirayama, Keiko Maeda, Kazuhiro Morise, Masanobu Matsushita, Kazuhiro Furukawa, Kohei Funasaka, Masanao Nakamura, Ryoji Miyahara, Naoki Ohmiya and Hidemi Goto |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Takafumi Ando, MD, PhD, Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya City, Aichi 466-8550, Japan. takafumiando-gi@umin.ac.jp |
| Key Words |
Ulcerative colitis; Cyclosporine; Maintenance therapy; Azathioprine; Long-term prognosis |
| Core Tip |
Cyclosporine is effective in avoiding emergency surgery in patients with severe steroid-refractory ulcerative colitis. However, few studies have evaluated long-term outcomes of cyclosporine therapy in Asia. This paper provides important information regarding the maintenance of steroid-free remission following cyclosporine therapy. Maintenance therapy with azathioprine improves the long-term efficacy of continuously infused cyclosporine in patients with severe steroid-refractory ulcerative colitis. |
| Publish Date |
2015-01-07 11:07 |
| Citation |
Miyake N, Ando T, Ishiguro K, Maeda O, Watanabe O, Hirayama Y, Maeda K, Morise K, Matsushita M, Furukawa K, Funasaka K, Nakamura M, Miyahara R, Ohmiya N, Goto H. Azathioprine is essential following cyclosporine for patients with steroid-refractory ulcerative colitis. World J Gastroenterol 2015; 21(1): 254-261 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i1/254.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i1.254 |
