Publication Name	World Journal of Clinical Cases
Manuscript ID	100735
Country	China

Received	2024-08-24 15:53
Peer-Review Started	2024-08-24 15:53
To Make the First Decision
Return for Revision	2024-10-28 07:43
Revised	2024-11-10 11:22
Second Decision	2024-12-09 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-09 08:40
Articles in Press	2024-12-09 08:40
Publication Fee Transferred	2024-11-12 09:23
Edit the Manuscript by Language Editor	2024-12-23 00:17
Typeset the Manuscript	2024-12-30 04:22
Publish the Manuscript Online	2025-01-11 13:23

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Hematology
Manuscript Type	Case Report
Article Title	Pegaspargase induced multiple organ failure with acute lymphoblastic leukemia: A case report.
Manuscript Source	Unsolicited Manuscript
All Author List	Su-Xia Bao, Xiao-Ling Yuan, Lei Yan and Jie Xu
ORCID	Author(s) ORCID Number Su-Xia Bao http://orcid.org/0000-0003-0412-832X Jie Xu http://orcid.org/0000-0002-9179-0049
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82100625 Zhejiang Provincial natural Science Foundation of China Q20H030013
Corresponding Author	Jie Xu, Department of Infectious Disease, Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, No 280 Mohe Road, Baoshan District, Shanghai 201900, China. dr.xu@aliyun.com
Key Words	Pegaspargase; Multiple organ failure; Acute lymphoblastic leukemia; Liver failure; Case report
Core Tip	We reported a rare patient with ALL, who suffered from multiple organ failure following the first application of pegaspargase. To date, only one patient had been reported and the patient died due to multiple organ failure in the reviewed word literature. In the article, although the patient had two rare phenomena reflecting poor prognosis, the patient was the first case of successful treatment. Two rare phenomena including inconformity between clinical manifestation and liver function, and persistent low AFP concentrations from subacute liver failure patients will be discussed in the patient.
Publish Date	2025-01-11 13:23
Citation	<p>Bao SX, Yuan XL, Yan L, Xu J. Pegaspargase induced multiple organ failure with acute lymphoblastic leukemia: A case report.. <i>World J Clin Cases</i> 2025; 13(13): 100735</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i13/100735.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i13.100735

Full Article (PDF)	WJCC-13-100735-with-cover.pdf
CARE Checklist–2016	100735-CARE-Checklist-2016.pdf
Manuscript File	100735_Auto_Edited_010708.docx
Answering Reviewers	100735-answering-reviewers.pdf
Audio Core Tip	100735-audio.wav
Conflict-of-Interest Disclosure Form	100735-conflict-of-interest-statement.pdf
Copyright License Agreement	100735-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	100735-foundation-statement.pdf
Signed Consent for Treatment Form(s) or Document(s)	100735-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	100735-non-native-speakers.pdf
Supplementary Material	100735-supplementary-material.pdf
Peer-review Report	100735-peer-reviews.pdf
Scientific Misconduct Check	100735-scientific-misconduct-check.png
Scientific Editor Work List	100735-scientific-editor-work-list.pdf
CrossCheck Report	100735-crosscheck-report.pdf