Publication Name	World Journal of Psychiatry
Manuscript ID	100738
Country	India

Received	2024-08-24 16:53
Peer-Review Started	2024-08-24 16:53
To Make the First Decision
Return for Revision	2024-11-18 08:19
Revised	2024-11-30 15:13
Second Decision	2024-12-20 03:07
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-20 07:32
Articles in Press	2024-12-20 07:32
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-12-24 11:32
Typeset the Manuscript	2024-12-30 04:35
Publish the Manuscript Online	2025-01-14 08:49

ISSN	2220-3206 (online)
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Category	Clinical Neurology
Manuscript Type	Retrospective Cohort Study
Article Title	Sodium channel mutation SCN1A T875M, D188V and associated dysfunction with drug resistant epilepsy
Manuscript Source	Invited Manuscript
All Author List	Pradeep Kumar Dabla, Swapan Gupta, Swati Singh, Aroop Viswas, Manisha Yadav, Subash Chandra Sonkar and Bidhan Chandra Koner
ORCID	Author(s) ORCID Number Pradeep Kumar Dabla http://orcid.org/0000-0003-1409-6771
Funding Agency and Grant Number
Corresponding Author	Pradeep Kumar Dabla, MBBS, MD, Professor, Department of Biochemistry, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, 1, Jawaharlal Nehru Marg, 64 Khamba, Raj Ghat, New Delhi 110002, Delhi, India. pradeep_dabla@yahoo.com
Key Words	Epilepsy; Single nucleotide polymorphisms; Drug-resistant epilepsy; SCN1A receptor; SCN1A rs121918623 and SCN1A rs121917953 gene polymorphism
Core Tip	Epilepsy is the most common paroxysmal neurological disorder with significant global health burden. A subset of patients are resistant to anti-epileptic drugs, leading to increased mortality and decreased quality of life. Mutations in genes encoding neuronal voltage-gated sodium channels have been linked to inherited forms of epilepsy. This study investigates the correlation between SCN1A gene variants rs121918623 and SCN1A rs121917953 and drug resistance in epilepsy suggesting specific genotypes as potential biomarkers in drug-resistant idiopathic epilepsy.
Publish Date	2025-01-14 08:49
Citation	<p>Dabla PK, Gupta S, Singh S, Viswas A, Yadav M, Sonkar SC, Koner BC. Sodium channel mutation SCN1A T875M, D188V and associated dysfunction with drug resistant epilepsy. <i>World J Psychiatry</i> 2025; 15(2): 100738</p>
URL	https://www.wjgnet.com/2220-3206/full/v15/i2/100738.htm
DOI	https://dx.doi.org/10.5498/wjp.v15.i2.100738

Full Article (PDF)	WJP-15-100738-with-cover.pdf
STROBE Statement	100738-STROBE-statement.pdf
Manuscript File	100738_Auto_Edited_010032.docx
Answering Reviewers	100738-answering-reviewers.pdf
Audio Core Tip	100738-audio.mp3
Biostatistics Review Certificate	100738-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	100738-conflict-of-interest-statement.pdf
Copyright License Agreement	100738-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	100738-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	100738-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	100738-non-native-speakers.pdf
Peer-review Report	100738-peer-reviews.pdf
Scientific Misconduct Check	100738-scientific-misconduct-check.png
Scientific Editor Work List	100738-scientific-editor-work-list.pdf
CrossCheck Report	100738-crosscheck-report.png
CrossCheck Report	100738-crosscheck-report.pdf