| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Microbiota in patients with cefuroxime resistance and anal fistula revealed by 16S ribosomal DNA
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Ting Ling, Fei Yao, Sen-Juan Li, Chen-Xi Cao, Zhen-Wei Chen, Min Qiu, Bu-Zhuo Li, Bi-Wen Hu, Shen-Yan Zhong, Guang-Lei Hu and Jia-Hua Li |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Jiaxing Science and Technology Project |
No. 2023AD11016 and No. 2023AD31028 |
|
| Corresponding Author |
Fei Yao, MD, Department of Anorectal Surgery, The Second Affiliated Hospital of Jiaxing University, No. 397 North Huancheng Road, Nanhu District, Jiaxing 314000, Zhejiang Province, China. yaof890726@163.com |
| Key Words |
Intestinal flora; Cefuroxime; Resistant; Anal fistula; 16S ribosomal DNA |
| Core Tip |
This study explores the role of gut microbiota in cefuroxime resistance among anal fistula patients, highlighting the protective effects of butyrate-producing bacteria such as Butyricicoccus and Roseburia. The findings demonstrate that modulating gut microbiota through probiotic intervention can significantly reduce cefuroxime resistance, improve stool consistency, and lower bowel movement frequency. This research offers valuable insights into the potential of microbiota-based strategies to manage antibiotic resistance and enhance perioperative care in anal fistula patients. |
| Publish Date |
2024-12-27 13:37 |
| Citation |
<p>Ling YT, Yao F, Li SJ, Cao CX, Chen ZW, Qiu M, Li BZ, Hu BW, Zhong SY, Hu GL, Li JH. Microbiota in patients with cefuroxime resistance and anal fistula revealed by 16S ribosomal DNA. <i>World J Gastrointest Surg</i> 2025; 17(1): 100790</p> |
| URL |
https://www.wjgnet.com/1948-9366/full/v17/i1/100790.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v17.i1.100790 |
