Publication Name	World Journal of Clinical Oncology
Manuscript ID	100807
Country	Spain

Received	2024-08-26 19:32
Peer-Review Started	2024-08-26 19:32
To Make the First Decision
Return for Revision	2024-09-17 02:45
Revised	2024-09-30 20:01
Second Decision	2024-10-23 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-23 13:01
Articles in Press	2024-10-23 13:01
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-10-30 22:51
Typeset the Manuscript	2024-11-25 09:49
Publish the Manuscript Online	2024-12-11 10:19

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Editorial
Article Title	Current and future perspectives in the management and treatment of colorectal cancer
Manuscript Source	Invited Manuscript
All Author List	Sigfredo E Romero-Zoghbi, Evita Krumina, Fernando López-Campos and Felipe Couñago
ORCID	Author(s) ORCID Number Sigfredo E Romero-Zoghbi http://orcid.org/0000-0002-7303-707X Evita Krumina http://orcid.org/0009-0005-7579-1294 Fernando López-Campos http://orcid.org/0000-0002-4077-0507 Felipe Couñago http://orcid.org/0000-0001-7233-0234
Funding Agency and Grant Number
Corresponding Author	Felipe Couñago, MD, PhD, Department of Radiation Oncology, GenesisCare-San Francisco de Asís University Hospital, Calle de Joaquín Costa, 28, Madrid 28002, Spain. felipe.counago@genesiscare.es
Key Words	Colorectal cancer; Metastatic colorectal cancer; Total neoadjuvant therapy; Chemoradiotherapy; Colon surgery; Rectal surgery; Chemotherapy; Immunotherapy
Core Tip	The management of colorectal cancer remains a challenge, but recent advances in total neoadjuvant therapy for advanced rectal cancer and the growing role of immunotherapy in tumors with high microsatellite instability or deficient mismatch repair are transforming the landscape. Modern treatments include new surgical techniques, advanced radiotherapy, and therapies targeting specific mutational profiles. Additionally, circulating tumor DNA is emerging as a crucial tool in precision oncology, improving prognosis and personalizing clinical care.
Publish Date	2024-12-11 10:19
Citation	<p>Romero-Zoghbi SE, Krumina E, López-Campos F, Couñago F. Current and future perspectives in the management and treatment of colorectal cancer. <i>World J Clin Oncol</i> 2025; 16(2): 100807</p>
URL	https://www.wjgnet.com/2218-4333/full/v16/i2/100807.htm
DOI	https://dx.doi.org/10.5306/wjco.v16.i2.100807

Full Article (PDF)	WJCO-16-100807-with-cover.pdf
Manuscript File	100807_Auto_Edited_030357.docx
Answering Reviewers	100807-answering-reviewers.pdf
Audio Core Tip	100807-audio.m4a
Conflict-of-Interest Disclosure Form	100807-conflict-of-interest-statement.pdf
Copyright License Agreement	100807-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	100807-non-native-speakers.pdf
Peer-review Report	100807-peer-reviews.pdf
Scientific Misconduct Check	100807-scientific-misconduct-check.png
Scientific Editor Work List	100807-scientific-editor-work-list.pdf
CrossCheck Report	100807-crosscheck-report.png
CrossCheck Report	100807-crosscheck-report.pdf