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2/24/2025 9:27:11 AM | Browse: 36 | Download: 79
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 100820
Country China
Received
2024-12-13 10:41
Peer-Review Started
2024-12-13 10:41
To Make the First Decision
Return for Revision
2025-01-09 05:12
Revised
2025-01-20 06:39
Second Decision
2025-02-06 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-02-07 01:12
Articles in Press
2025-02-07 01:12
Publication Fee Transferred
2025-01-24 15:19
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-02-12 01:15
Publish the Manuscript Online
2025-02-24 09:27
ISSN 1948-9366 (online)
Open Access Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Retrospective analysis of preoperative tumor marker levels in rectal cancer patients: Implications for diagnosis
Manuscript Source Unsolicited Manuscript
All Author List Ming Li, Da-Hao Yuan, Zhi Yang, Teng-Xiang Lu and Lei Zhang
ORCID
Author(s) ORCID Number
Ming Li http://orcid.org/0009-0003-4704-8925
Lei Zhang http://orcid.org/0009-0009-3640-5150
Funding Agency and Grant Number
Corresponding Author Lei Zhang, Associate Chief Physician, Department of Gastrointestinal Surgery, Linquan County People’s Hospital, No. 206 Jianshe South Road, Linquan 236400, Anhui Province, China. zlmale8902@sina.com
Key Words Rectal cancer; Tumor markers; Carcinoembryonic antigen; Cancer antigen 19-9; Cancer antigen 72-4; Fecal occult blood test; Diagnosis
Core Tip This study highlights the effectiveness of a multi-marker approach for the preoperative diagnosis of rectal cancer. Analysis of serum levels of the tumor markers carcinoembryonic antigen, cancer antigen 19-9, and cancer antigen 72-4, along with fecal occult blood testing, demonstrated improved diagnostic accuracy, with an area under the curve of 0.91. Significant correlations between elevated carcinoembryonic antigen levels and clinicopathological features, such as tumor stage and lymph node involvement, suggest that this combined strategy could enhance the risk stratification and management of patients with rectal cancer, ultimately aiding in earlier detection and better clinical outcomes.
Publish Date 2025-02-24 09:27
Citation <p>Li M, Yuan DH, Yang Z, Lu TX, Zhang L. Retrospective analysis of preoperative tumor marker levels in rectal cancer patients: Implications for diagnosis. <i>World J Gastrointest Surg</i> 2025; 17(3): 100820</p>
URL https://www.wjgnet.com/1948-9366/full/v17/i3/100820.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i3.100820
Full Article (PDF) WJGS-17-100820-with-cover.pdf
Manuscript File 100820_Auto_Edited_015853.docx
Answering Reviewers 100820-answering-reviewers.pdf
Audio Core Tip 100820-audio.m4a
Biostatistics Review Certificate 100820-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 100820-conflict-of-interest-statement.pdf
Copyright License Agreement 100820-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 100820-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 100820-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 100820-non-native-speakers.pdf
Peer-review Report 100820-peer-reviews.pdf
Scientific Misconduct Check 100820-scientific-misconduct-check.png
Scientific Editor Work List 100820-scientific-editor-work-list.pdf
CrossCheck Report 100820-crosscheck-report.pdf