Publication Name	World Journal of Gastroenterology
Manuscript ID	100827
Country	China

Received	2024-08-28 06:45
Peer-Review Started	2024-09-05 03:47
To Make the First Decision
Return for Revision	2024-09-20 01:00
Revised	2024-09-30 07:20
Second Decision	2024-11-15 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-15 05:57
Articles in Press	2024-11-15 05:57
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-11-19 04:11
Typeset the Manuscript	2024-12-01 02:12
Publish the Manuscript Online	2024-12-18 07:36

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Medicine, Research & Experimental
Manuscript Type	Letter to the Editor
Article Title	Exploring gut microbiota as a novel therapeutic target in Crohn’s disease: Insights and emerging strategies
Manuscript Source	Invited Manuscript
All Author List	Tong Qiao and Xian-Hui Wen
ORCID	Author(s) ORCID Number Xian-Hui Wen http://orcid.org/0009-0002-0905-8738
Funding Agency and Grant Number
Corresponding Author	Xian-Hui Wen, PhD, College of Life Science and Technology, Jinan University, No. 601 Huangpu Avenue West, Tianhe District, Guangzhou 510632, Guangdong Province, China. 17818521036@163.com
Key Words	Crohn’s disease; Gut microbiome; Dysbiosis; Creeping fat; Fecal microbiota transplantation
Core Tip	Crohn’s disease (CD) represents a complex and challenging medical condition, characterized by the intricate interplay between genetic predisposition, gut microbiota dysbiosis, and immune dysregulation. We have discussed the key effects of gut microbiota on CD, as well as how they affect creeping fat. Furthermore, we highlight the urgent need to address gut microbiota imbalances, particularly focusing on pathogenic species and their mechanisms, as a critical therapeutic target. Our findings underscore the importance of a personalized approach to CD management, emphasizing the need for continued research and innovation to address this complex disease.
Publish Date	2024-12-18 07:36
Citation	<p>Qiao T, Wen XH. Exploring gut microbiota as a novel therapeutic target in Crohn’s disease: Insights and emerging strategies. <i>World J Gastroenterol</i> 2025; 31(2): 100827</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i2/100827.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i2.100827

Full Article (PDF)	WJG-31-100827-with-cover.pdf
Manuscript File	100827_Auto_Edited_035332.docx
Answering Reviewers	100827-answering-reviewers.pdf
Audio Core Tip	100827-audio.mp3
Conflict-of-Interest Disclosure Form	100827-conflict-of-interest-statement.pdf
Copyright License Agreement	100827-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	100827-non-native-speakers.pdf
Peer-review Report	100827-peer-reviews.pdf
Scientific Misconduct Check	100827-scientific-misconduct-check.png
Scientific Editor Work List	100827-scientific-editor-work-list.pdf
CrossCheck Report	100827-crosscheck-report.pdf