Publication Name	World Journal of Gastroenterology
Manuscript ID	100834
Country	United States

Received	2024-08-28 06:54
Peer-Review Started	2024-09-06 06:03
To Make the First Decision
Return for Revision	2024-10-12 22:38
Revised	2024-10-17 20:15
Second Decision	2024-11-05 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-05 05:20
Articles in Press	2024-11-05 05:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-08 02:55
Publish the Manuscript Online	2024-11-21 07:04

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Fanlian Huazhuo Formula: A promising herbal preparation for metabolic liver disease
Manuscript Source	Invited Manuscript
All Author List	Bhupesh Singla
ORCID	Author(s) ORCID Number Bhupesh Singla http://orcid.org/0000-0003-2752-6849
Funding Agency and Grant Number	Funding Agency Grant Number National Institutes of Health Grants K99HL146954 National Institutes of Health Grants R00HL146954 College of Pharmacy Seed Research Grant Program of the University of Tennessee Health Science Center
Corresponding Author	Bhupesh Singla, Assistant Professor, PhD, Pharmaceutical Sciences, The University of Tennessee Health Science Center, 881 Madison Ave, Room 446, Memphis, TN 38103, United States. bsingla@uthsc.edu
Key Words	Metabolic dysfunction-associated steatotic liver disease; Fanlian Huazhuo Formula; De novo lipogenesis; Cell death; Adenosine-5’-monophosphate-activated protein kinase alpha; Acetyl-CoA carboxylase
Core Tip	Various constituents of Fanlian Huazhuo Formula (FLHZF) have been shown to regulate several metabolic and inflammatory parameters in diabetic mice, including hepatic lipid metabolism and injury, body weight, adipose tissue inflammation, and gut microbiota. Niu et al reported novel insights into the therapeutic benefits of FLHZF in diet-induced metabolic dysfunction-associated steatotic liver disease using various complementary approaches. However, future studies are required to better understand the underlying molecular mechanisms, determine the therapeutic efficacy of FLHZF in other models, and rule out its sex-specific benefits.
Publish Date	2024-11-21 07:04
Citation	<p>Singla B. Fanlian Huazhuo Formula: A promising herbal preparation for metabolic liver disease. <i>World J Gastroenterol</i> 2024; 30(46): 4964-4968</p>
URL	https://www.wjgnet.com/1007-9327/full/v30/i46/4964.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i46.4964

Full Article (PDF)	WJG-30-4964-with-cover.pdf
Manuscript File	100834_Auto_Edited_054532.docx
Answering Reviewers	100834-answering-reviewers.pdf
Audio Core Tip	100834-audio.mp3
Conflict-of-Interest Disclosure Form	100834-conflict-of-interest-statement.pdf
Copyright License Agreement	100834-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	100834-foundation-statement.pdf
Peer-review Report	100834-peer-reviews.pdf
Scientific Misconduct Check	100834-scientific-misconduct-check.png
Scientific Editor Work List	100834-scientific-editor-work-list.pdf
CrossCheck Report	100834-crosscheck-report.pdf