| ISSN |
2220-3206 (online) |
| Open Access |
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Prospective Study |
| Article Title |
Who can benefit more from its twelve-week treatment: A prospective cohort study of blonanserin for patients with schizophrenia
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bao-Yan Xu, Kun Jin, Hai-Shan Wu, Xue-Jun Liu, Xi-Jin Wang, Hong Sang, Ke-Qing Li, Mei-Juan Sun, Hua-Qing Meng, Huai-Li Deng, Zhi-Yuan Xun, Xiao-Dong Yang, Lin Zhang, Guan-Jun Li, Rui-Ling Zhang, Duan-Fang Cai, Jia-Hong Liu, Gui-Jun Zhao, Long-Fa Liu, Gang Wang, Chang-Lie Zhao, Bin Guo, Sheng-Chun Jin, Ling-Yun Huang, Fu-De Yang, Jian-Min Zheng, Gui-Lai Zhan, Mao-Sheng Fang, Xiang-Jun Meng, Guang-Ya Zhang, Hai-Min Li, Xiang-Lai Liu, Ju-Hong Li, Bin Wu, Hai-Yun Li and Jin-Dong Chen |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jin-Dong Chen, PhD, Professor, Department of Psychiatry, National Clinical Research Center for Mental Disorders, National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, No. 139 Middle Renmin Road, Changsha 410011, Hunan Province, China. chenjindong@csu.edu.cn |
| Key Words |
Schizophrenia; Blonanserin; Effectiveness; Psychosocial functioning; Prospective cohort study |
| Core Tip |
This analysis included a large sample of 3306 patients with schizophrenia from the first post-marketing surveillance of blonanserin (BNS) in China. Our aim was to explore factors influencing treatment outcomes to assist in the early identification of patients with schizophrenia who are suitable for specific treatments like BNS. We found that patients in the acute phase with more severe symptoms, shorter current episode duration, and fewer previous episodes who were treated with a lower dose of concomitant antipsychotics and fewer types of sedative-hypnotic agents benefited the most from BNS treatment. These results provide valuable evidence for more a reasonable application of BNS in China. |
| Publish Date |
2024-11-07 08:33 |
| Citation |
<p>Xu BY, Jin K, Wu HS, Liu XJ, Wang XJ, Sang H, Li KQ, Sun MJ, Meng HQ, Deng HL, Xun ZY, Yang XD, Zhang L, Li GJ, Zhang RL, Cai DF, Liu JH, Zhao GJ, Liu LF, Wang G, Zhao CL, Guo B, Jin SC, Huang LY, Yang FD, Zheng JM, Zhan GL, Fang MS, Meng XJ, Zhang GY, Li HM, Liu XL, Li JH, Wu B, Li HY, Chen JD. Who can benefit more from its twelve-week treatment: A prospective cohort study of blonanserin for patients with schizophrenia. <i>World J Psychiatry</i> 2024; 14(11): 1735-1745</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v14/i11/1735.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v14.i11.1735 |
