ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Observational Study |
Article Title |
Hemoglobin glycation index among adults with type 1 diabetes: Association with double diabetes features
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Xiao-Lin Ji, Min Yin, Chao Deng, Li Fan, Yu-Ting Xie, Fan-Su Huang, Yan Chen and Xia Li |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Key R D Program of China |
No. 2022YFC2010102 |
Natural Science Foundation of Hunan Province |
No. 2021JC0003 |
National Natural Science Foundation of China |
No. 82070812 |
Sinocare Diabetes Foundation |
No. LYF2022039 |
|
Corresponding Author |
Xia Li, PhD, Professor, National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology (Central South University), Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, No. 139 Renmin Middle Road, Furong District, Changsha 410011, Hunan Province, China. lixia@csu.edu.cn |
Key Words |
Type 1 diabetes; Double diabetes; Insulin resistance; Hemoglobin glycation index; Advanced glycation end products; Diabetic complications |
Core Tip |
Insights into the discrepancy between the mean blood glucose and laboratory glycated hemoglobin (HbA1c) levels in patients with type 1 diabetes (T1D) are limited. This study aimed to quantify this discrepancy by calculating the hemoglobin glycation index (HGI) based on laboratory HbA1c and continuous glucose monitoring-derived mean blood glucose levels. The results indicated that double diabetes features in in patients with T1D are associated with a higher HGI, which represents a trend toward excessive glycosylation and is associated with a higher prevalence of chronic diabetic complications. |
Publish Date |
2025-02-28 10:46 |
Citation |
<p>Ji XL, Yin M, Deng C, Fan L, Xie YT, Huang FS, Chen Y, Li X. Hemoglobin glycation index among adults with type 1 diabetes: Association with double diabetes features. <i>World J Diabetes</i> 2025; 16(4): 100917</p> |
URL |
https://www.wjgnet.com/1948-9358/full/v16/i4/100917.htm |
DOI |
https://dx.doi.org/10.4239/wjd.v16.i4.100917 |