Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	100927
Country	China

Received	2024-08-30 11:31
Peer-Review Started	2024-08-30 11:31
To Make the First Decision
Return for Revision	2024-11-24 02:51
Revised	2024-12-06 14:37
Second Decision	2024-12-24 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-25 11:18
Articles in Press	2024-12-25 11:18
Publication Fee Transferred	2024-12-12 05:07
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-01-22 05:46
Publish the Manuscript Online	2025-02-14 10:33

ISSN	1948-5204 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Hypercoagulation after neoadjuvant immunochemotherapy as a new prognostic indicator in patients with locally advanced gastric cancer undergoing surgery
Manuscript Source	Unsolicited Manuscript
All Author List	Tian-Hao Li, Xiong Sun, Cheng-Guo Li, Yu-Ping Yin and Kai-Xiong Tao
ORCID	Author(s) ORCID Number Tian-Hao Li http://orcid.org/0009-0002-6963-4469 Yu-Ping Yin http://orcid.org/0000-0003-4568-8315 Kai-Xiong Tao http://orcid.org/0000-0002-7723-6121
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82072736, 82003205, 82373123 and 82473175 Key Research and Development Program of Hubei Province of China No. 2021BCA116 Natural Science Foundation of Hubei Province of China No. 2024AFB655
Corresponding Author	Yu-Ping Yin, MD, PhD, Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. yinyuping2017@hust.edu.cn
Key Words	Locally advanced gastric cancer; Coagulation; Neoadjuvant immunochemotherapy; Prognosis; Radical gastrectomy
Core Tip	This retrospective study assessed the correlation between hypercoagulation after neoadjuvant immunochemotherapy (NICT) and the prognosis of patients with locally advanced gastric cancer (LAGC). Results indicated that the non-hypercoagulation group exhibited significantly superior overall survival (OS) and disease-free survival (DFS) rates compared with the hypercoagulation group. Furthermore, multivariate analysis revealed that hypercoagulation after NICT was an independent risk factor for adverse postoperative OS and DFS. This suggests that hypercoagulation after NICT is an independent prognostic indicator of LAGC and may be used to evaluate therapeutic effects.
Publish Date	2025-02-14 10:33
Citation	<p>Li TH, Sun X, Li CG, Yin YP, Tao KX. Hypercoagulation after neoadjuvant immunochemotherapy as a new prognostic indicator in patients with locally advanced gastric cancer undergoing surgery. <i>World J Gastrointest Oncol</i> 2025; 17(3): 100927</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i3/100927.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i3.100927

Full Article (PDF)	WJGO-17-100927-with-cover.pdf
Manuscript File	100927_Auto_Edited_005712.docx
Answering Reviewers	100927-answering-reviewers.pdf
Audio Core Tip	100927-audio.mp3
Biostatistics Review Certificate	100927-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	100927-conflict-of-interest-statement.pdf
Copyright License Agreement	100927-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	100927-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	100927-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	100927-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	100927-non-native-speakers.pdf
Supplementary Material	100927-supplementary-material.pdf
Peer-review Report	100927-peer-reviews.pdf
Scientific Misconduct Check	100927-scientific-misconduct-check.png
Scientific Editor Work List	100927-scientific-editor-work-list.pdf
CrossCheck Report	100927-crosscheck-report.pdf