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11/21/2024 7:04:50 AM | Browse: 75 | Download: 248
Publication Name World Journal of Gastroenterology
Manuscript ID 101045
Country Canada
Received
2024-09-02 23:08
Peer-Review Started
2024-09-02 23:08
To Make the First Decision
Return for Revision
2024-09-20 00:54
Revised
2024-10-10 16:26
Second Decision
2024-11-04 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-11-04 07:14
Articles in Press
2024-11-04 07:14
Publication Fee Transferred
2024-11-06 01:05
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-11-12 06:24
Publish the Manuscript Online
2024-11-21 07:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Real-world experience and long-term outcomes of a mandatory non-medical switch of adalimumab originator to biosimilars in inflammatory bowel disease
Manuscript Source Unsolicited Manuscript
All Author List Jeremy Liu Chen Kiow, Thomas Hoang, Harjot K Bedi, Zhina Majdzadeh Ardekani, Daniel Rosenfeld, Marica Reise-Filteau, Brian Bressler, Yvette Leung and Greg Rosenfeld
ORCID
Author(s) ORCID Number
Jeremy Liu Chen Kiow http://orcid.org/0000-0003-2486-3647
Harjot K Bedi http://orcid.org/0000-0002-1328-9152
Brian Bressler http://orcid.org/0000-0003-4740-8209
Funding Agency and Grant Number
Corresponding Author Jeremy Liu Chen Kiow, MD, Department of Medicine, Division of Gastroenterology, Montreal University Hospital Centre (CHUM), 1051 Rue Sanguinet, Montreal H2X 3E4, Quebec, Canada. jeremy.liu.chen.kiow@umontreal.ca
Key Words Inflammatory bowel disease; Ulcerative colitis; Crohn’s disease; Biologics; Adalimumab; Biosimilar switch
Core Tip Although there have been several studies evaluating the short-term clinical outcomes of adalimumab (ADA) biosimilar switching, there has been a lack of data assessing the long-term outcomes, especially in Canada. Non-medical switching of the ADA originator to biosimilars did not result in significant differences in treatment persistence, loss of response, or adverse events compared to ADA originator continuation in inflammatory bowel disease (IBD). The findings from this real-world evidence study support the long-term efficacy and safety of non-medical ADA switching in IBD. These data will help inform patients and physicians in jurisdictions currently undergoing biosimilar switching and guide future biosimilar adoption and practice guidelines.
Publish Date 2024-11-21 07:04
Citation <p>Liu Chen Kiow J, Hoang T, Bedi HK, Majdzadeh Ardekani Z, Rosenfeld D, Reise-Filteau M, Bressler B, Leung Y, Rosenfeld G. Real-world experience and long-term outcomes of a mandatory non-medical switch of adalimumab originator to biosimilars in inflammatory bowel disease. <i>World J Gastroenterol</i> 2024; 30(46): 4904-4913</p>
URL https://www.wjgnet.com/1007-9327/full/v30/i46/4904.htm
DOI https://dx.doi.org/10.3748/wjg.v30.i46.4904
Full Article (PDF) WJG-30-4904-with-cover.pdf
STROBE Statement 101045-STROBE-statement.pdf
Manuscript File 101045_Auto_Edited_062500.docx
Answering Reviewers 101045-answering-reviewers.pdf
Audio Core Tip 101045-audio.wav
Biostatistics Review Certificate 101045-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 101045-conflict-of-interest-statement.pdf
Copyright License Agreement 101045-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 101045-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 101045-institutional-review-board-statement.pdf
Peer-review Report 101045-peer-reviews.pdf
Scientific Misconduct Check 101045-scientific-misconduct-check.png
Scientific Editor Work List 101045-scientific-editor-work-list.pdf
CrossCheck Report 101045-crosscheck-report.png
CrossCheck Report 101045-crosscheck-report.pdf