Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	101060
Country	China

Received	2024-09-03 08:28
Peer-Review Started	2024-09-03 08:28
To Make the First Decision
Return for Revision	2025-01-09 07:43
Revised	2025-01-17 06:44
Second Decision	2025-02-06 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-07 00:39
Articles in Press	2025-02-07 00:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-02-12 00:44
Publish the Manuscript Online	2025-02-24 09:27

ISSN	1948-9366 (online)
Open Access	Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Editorial
Article Title	Hyperthermia combined with opioid therapy: Enhancing cancer pain management and reducing surgical stress in gastrointestinal cancer patients
Manuscript Source	Invited Manuscript
All Author List	Yue Wang, Xin Xun, Wen-Yu Luan, Zheng Zhang, Zhen-Xi Xu, Si-Xiang Lin and Yan-Dong Miao
ORCID	Author(s) ORCID Number Wen-Yu Luan http://orcid.org/0009-0007-8093-1356 Yan-Dong Miao http://orcid.org/0000-0002-1429-8915
Funding Agency and Grant Number	Funding Agency Grant Number Science and Technology Program of Yantai Affiliated Hospital of Binzhou Medical University YTFY2022KYQD06 The Shandong Province Medical and Health Science and Technology Development Plan Project 202203030713
Corresponding Author	Yan-Dong Miao, Associate Professor, MD, Department of Cancer Center, Yantai Affiliated Hospital of Binzhou Medical University, The Second Medical College of Binzhou Medical University, No. 717 Jinbu Street, Muping District, Yantai 264100, Shandong Province, China. miaoyd_22@bzmc.edu.cn
Key Words	Gastrointestinal cancer; Hyperthermia; Opioid therapy; Cancer pain management; Surgical stress reduction; Enhanced recovery; Adverse reactions; Pain control
Core Tip	This article highlights a novel combination therapy involving hyperthermia and opioid treatment for managing cancer-related pain in gastrointestinal cancer patients. The approach has shown promising results in enhancing pain control, reducing opioid dosage, and minimizing adverse reactions. The integration of hyperthermia not only improves pain management but also aids in reducing surgical stress and accelerating recovery. The article advocates for further research to fully understand the mechanisms at play and to explore broader clinical applications, potentially setting a new standard in oncological care.
Publish Date	2025-02-24 09:27
Citation	<p>Wang Y, Xun X, Luan WY, Zhang Z, Xu ZX, Lin SX, Miao YD. Hyperthermia combined with opioid therapy: Enhancing cancer pain management and reducing surgical stress in gastrointestinal cancer patients. <i>World J Gastrointest Surg</i> 2025; 17(3): 101060</p>
URL	https://www.wjgnet.com/1948-9366/full/v17/i3/101060.htm
DOI	https://dx.doi.org/10.4240/wjgs.v17.i3.101060

Full Article (PDF)	WJGS-17-101060-with-cover.pdf
Manuscript File	101060_Auto_Edited_015834.docx
Answering Reviewers	101060-answering-reviewers.pdf
Audio Core Tip	101060-audio.m4a
Conflict-of-Interest Disclosure Form	101060-conflict-of-interest-statement.pdf
Copyright License Agreement	101060-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	101060-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	101060-non-native-speakers.pdf
Peer-review Report	101060-peer-reviews.pdf
Scientific Misconduct Check	101060-scientific-misconduct-check.png
Scientific Editor Work List	101060-scientific-editor-work-list.pdf
CrossCheck Report	101060-crosscheck-report.pdf