Publication Name	World Journal of Gastroenterology
Manuscript ID	10108
Country	Spain

Received	2014-03-14 08:52
Peer-Review Started
To Make the First Decision
Return for Revision
Revised
Second Decision	2014-04-09 09:17
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-09 10:57
Articles in Press	2014-05-23 09:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-24 16:24
Publish the Manuscript Online	2014-08-18 16:49

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, Research & Experimental
Manuscript Type	Topic Highlights
Article Title	Optimizing clarithromycin-containing therapy for Helicobacter pylori in the era of antibiotic resistance
Manuscript Source	Invited Manuscript
All Author List	Javier Molina-Infante and Javier P Gisbert
Funding Agency and Grant Number
Corresponding Author	Javier Molina-Infante, MD, Department of Gastroenterology, Hospital San Pedro de Alcantara, C/ Pablo Naranjo s/n, 10003 Caceres, Spain. xavi_molina@hotmail.com
Key Words	Helicobacter pylori; Eradication; Clarithromycin; Sequential; Concomitant; Hybrid; Antibiotic resistance; Bismuth
Core Tip	Triple therapy is no longer effective to eradicate Helicobacter pylori infection in most settings across the world. Bismuth quadruple therapy has resurfaced as an ideal replacement, despite its implementation in clinical practice may be troublesome. As such, non-bismuth quadruple therapies remain in the therapeutic front line in clinical practice. This article updates available evidence over the last five years on the efficacy of several non-bismuth quadruple schemes and different tools used to optimize them, providing a novel regionalized therapeutic algorithm, according to novel predicting models based on local antibiotic resistance rates.
Publish Date	2014-08-18 16:49
Citation	Molina-Infante J, Gisbert JP. Optimizing clarithromycin-containing therapy for Helicobacter pylori in the era of antibiotic resistance. World J Gastroenterol 2014; 20(30): 10338-10347
URL	http://www.wjgnet.com/1007-9327/full/v20/i30/10338.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i30.10338

Full Article (PDF)	WJG-20-10338.pdf
Full Article (Word)	WJG-20-10338.doc
Manuscript File	10108-Review.docx
Answering Reviewers	10108-Answering reviewers.pdf
Copyright License Agreement	10108-Copyright assignment.pdf
Peer-review Report	10108-Peer review(s).pdf
Scientific Editor Work List	10108-Scientific editor work list.doc