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1/21/2025 9:22:08 AM | Browse: 84 | Download: 365
Publication Name World Journal of Clinical Oncology
Manuscript ID 101098
Country China
Received
2024-09-04 07:47
Peer-Review Started
2024-09-04 07:47
First Decision by Editorial Office Director
2024-11-18 09:18
Return for Revision
2024-11-18 09:18
Revised
2024-11-30 09:00
Publication Fee Transferred
Second Decision by Editor
2024-12-17 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2024-12-17 08:48
Articles in Press
2024-12-17 08:48
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-01-13 01:49
Publish the Manuscript Online
2025-01-21 09:22
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Editorial
Article Title Incorporation of human β-defensin-1 into immunoliposomes to facilitate targeted autophagy therapy of colon carcinoma
Manuscript Source Invited Manuscript
All Author List Ying Huang, Xi-Ye Wang, Jia-Yue Huang and Zheng-Wei Huang
ORCID
Author(s) ORCID Number
Zheng-Wei Huang http://orcid.org/0000-0003-2351-7347
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China No. 82104070
Guangdong Universities Keynote Regions Special Funded Project No. 2022ZDZX2002
Corresponding Author Zheng-Wei Huang, Associate Professor, PhD, College of Pharmacy, Jinan University, No. 855 East Xingye Dadao, Panyu District, Guangzhou 511443, Guangdong Province, China. huangzhengw@jnu.edu.cn
Key Words Human β-defensin-1; Immunoliposomes; Colon cancer; SW620; Autophagy
Core Tip Nanotechnology is a cost-effective strategy for addressing the druggable properties of proteins. We propose an immunoliposome system that improves the stability, bioavailability and targeting properties of human β-defensin-1 (hBD-1), which will support its clinical translation. Our strategy is highly effective and may lead to positive clinical trials and large-scale production. We consider immunoliposomes to be suitable nanovesicles for enhancing the drug properties of hBD-1 and warrant further basic and translational research.
Publish Date 2025-01-21 09:22
Citation

Huang Y, Wang XY, Huang JY, Huang ZW. Incorporation of human β-defensin-1 into immunoliposomes to facilitate targeted autophagy therapy of colon carcinoma. World J Clin Oncol 2025; 16(3): 101098

URL https://www.wjgnet.com/2218-4333/full/v16/i3/101098.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i3.101098
Full Article (PDF) WJCO-16-101098-with-cover.pdf
Manuscript File 101098_Auto_Edited_083255.docx
Answering Reviewers 101098-answering-reviewers.pdf
Audio Core Tip 101098-audio.m4a
Conflict-of-Interest Disclosure Form 101098-conflict-of-interest-statement.pdf
Copyright License Agreement 101098-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 101098-non-native-speakers.pdf
Peer-review Report 101098-peer-reviews.pdf
Scientific Misconduct Check 101098-scientific-misconduct-check.png
Scientific Editor Work List 101098-scientific-editor-work-list.pdf
CrossCheck Report 101098-crosscheck-report.pdf