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Articles Published Processes
12/18/2024 8:36:39 AM | Browse: 47 | Download: 357
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Received |
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2024-09-05 03:53 |
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Peer-Review Started |
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2024-09-05 03:53 |
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To Make the First Decision |
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Return for Revision |
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2024-10-23 10:55 |
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Revised |
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2024-11-02 15:58 |
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Second Decision |
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2024-11-18 02:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-11-18 11:18 |
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Articles in Press |
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2024-11-18 11:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-11-27 08:22 |
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Publish the Manuscript Online |
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2024-12-18 08:36 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Editorial |
| Article Title |
Gut-brain axis as a bridge in obesity and depression: Mechanistic exploration and therapeutic prospects
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rui-Ying Fang, Xiao-Rui Pan, Xin-Xing Zeng, Zheng-Zheng Li, Bo-Fan Chen, Hai-Min Zeng and Jie Peng |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jie Peng, MD, The Second Clinical Medical College, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No. 1 Minde Road, Donghu District, Nanchang 330006, Jiangxi Province, China. jie_peng@email.ncu.edu.cn |
| Key Words |
Gut-brain axis; Obesity; Depression; Gut microbiota; Mechanism |
| Core Tip |
The gut-brain axis is a crucial pathway that links the intestines to the brain and influences host health through microbial metabolites, neural signals, immune responses, and endocrine pathways. Metabolic byproducts of microbes, such as short-chain fatty acids, lipopolysaccharide and bile acids, modulate appetite, emotional regulation, and immune-inflammatory responses via the gut-brain axis and are closely associated with the onset and progression of obesity and depression. Modulating the gut‒brain axis, for example, through the use of prebiotics, specific ketogenic diet, and the supplementation of antioxidants, provides new therapeutic strategies for obesity and depression. Future research needs to delve deeper into the mechanisms of the gut-brain axis to develop more effective interventions. |
| Publish Date |
2024-12-18 08:36 |
| Citation |
<p>Fang RY, Pan XR, Zeng XX, Li ZZ, Chen BF, Zeng HM, Peng J. Gut-brain axis as a bridge in obesity and depression: Mechanistic exploration and therapeutic prospects. <i>World J Psychiatry</i> 2025; 15(1): 101134</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i1/101134.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i1.101134 |
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