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Articles Published Processes
1/21/2025 6:56:15 AM | Browse: 50 | Download: 474
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Received |
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2024-09-05 10:06 |
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Peer-Review Started |
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2024-09-05 10:06 |
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First Decision by Editorial Office Director |
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2024-10-24 02:26 |
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Return for Revision |
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2024-10-24 02:26 |
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Revised |
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2024-11-06 22:57 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-12-02 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-12-02 08:18 |
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Articles in Press |
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2024-12-02 08:18 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-01-02 02:26 |
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Publish the Manuscript Online |
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2025-01-21 06:56 |
| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Editorial |
| Article Title |
Umbilical cord-derived mesenchymal stromal cells: Promising therapy for heart failure
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ya-Lun Li, En-Guo Chen and Bing-Bing Ren |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bing-Bing Ren, Associate Professor, PhD, Department of Pulmonary and Critical Care Medicine, Regional Medical Center for National Institute of Respiratory Disease, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, No. 3 East Qingchun Road, Hangzhou 310016, Zhejiang Province, China. renbb@ustc.edu.cn |
| Key Words |
Cardiovascular diseases; Heart failure; Cell therapy; Bone marrow-derived mesenchymal stromal cells; Umbilical cord-derived mesenchymal stromal cells |
| Core Tip |
There has been increased emphasis on the efficacy and potential of umbilical cord-derived mesenchymal stromal cells (UC-MSCs) for reversing cardiac remodeling in heart failure. UC-MSCs exhibit low immunogenicity and tumorigenicity, with a painless, non-invasive collection process. Compared to bone marrow-derived mesenchymal stromal cells, UC-MSCs exhibit superior proliferation, migration, immunosuppressive effects, and paracrine activity. However, their efficacy largely depends on the primitive source and extraction/delivery methods. Therefore, optimizing extraction/delivery techniques and conducting rigorous clinical trials are essential for further clinical implementation of UC-MSCs in heart failure patients. |
| Publish Date |
2025-01-21 06:56 |
| Citation |
Li YL, Chen EG, Ren BB. Umbilical cord-derived mesenchymal stromal cells: Promising therapy for heart failure. World J Cardiol 2025; 17(1): 101153 |
| URL |
https://www.wjgnet.com/1949-8462/full/v17/i1/101153.htm |
| DOI |
https://dx.doi.org/10.4330/wjc.v17.i1.101153 |
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