Publication Name	World Journal of Gastroenterology
Manuscript ID	101180
Country	China

Received	2024-09-06 08:12
Peer-Review Started	2024-09-06 08:12
To Make the First Decision
Return for Revision	2024-10-15 21:44
Revised	2024-10-26 15:49
Second Decision	2024-11-19 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-19 06:39
Articles in Press	2024-11-19 06:39
Publication Fee Transferred	2024-11-21 15:05
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-29 09:00
Publish the Manuscript Online	2024-12-18 07:36

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Association between intra-pancreatic fat deposition and diseases of the exocrine pancreas: A narrative review
Manuscript Source	Unsolicited Manuscript
All Author List	Jing Ye, Jian-Guo Wang, Rong-Qiang Liu, Qiao Shi and Wei-Xing Wang
ORCID	Author(s) ORCID Number Wei-Xing Wang http://orcid.org/0000-0002-3854-0083
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82170651 the Research Support Fund of Hubei Microcirculation Society HBWXH2024(1)-1
Corresponding Author	Wei-Xing Wang, MD, Professor, Department of General Surgery, Renmin Hospital of Wuhan University, No. 238 Jiefang Road, Wuhan 430060, Hubei Province, China. sate.llite@163.com
Key Words	Intrapancreatic fat deposition; Pancreatic steatosis; Nonalcoholic fatty pancreas disease; Pancreatitis; Pancreatic cancer
Core Tip	Intrapancreatic fat deposition (IPFD) is a prevalent and clinically significant condition linked to exocrine pancreatic diseases, obesity, age, and sex. Although the mechanisms driving IPFD remain poorly understood, factors like oxidative stress, gut microbiota alterations, and hormonal imbalances are thought to contribute. Imaging is currently the main diagnostic method, but emerging biomarkers and scoring systems offer new diagnostic avenues. While there are no established treatments, glucagon-like peptide-1 receptor agonists and novel experimental therapies show promise. This review highlights recent insights into IPFD’s pathogenesis, diagnosis, and therapeutic potential, underscoring its clinical importance in pancreatic health management.
Publish Date	2024-12-18 07:36
Citation	<p>Ye J, Wang JG, Liu RQ, Shi Q, Wang WX. Association between intra-pancreatic fat deposition and diseases of the exocrine pancreas: A narrative review. <i>World J Gastroenterol</i> 2025; 31(2): 101180</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i2/101180.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i2.101180

Full Article (PDF)	WJG-31-101180-with-cover.pdf
Manuscript File	101180_Auto_Edited_062030.docx
Answering Reviewers	101180-answering-reviewers.pdf
Audio Core Tip	101180-audio.mp3
Conflict-of-Interest Disclosure Form	101180-conflict-of-interest-statement.pdf
Copyright License Agreement	101180-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	101180-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	101180-non-native-speakers.pdf
Peer-review Report	101180-peer-reviews.pdf
Scientific Misconduct Check	101180-scientific-misconduct-check.png
Scientific Editor Work List	101180-scientific-editor-work-list.pdf
CrossCheck Report	101180-crosscheck-report.pdf