Publication Name	World Journal of Hepatology
Manuscript ID	101201
Country	China

Received	2024-09-09 06:07
Peer-Review Started	2024-09-10 06:19
To Make the First Decision
Return for Revision	2024-10-20 11:28
Revised	2024-11-13 17:13
Second Decision	2024-12-23 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-23 09:34
Articles in Press	2024-12-23 09:34
Publication Fee Transferred	2024-11-17 08:39
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-01-15 01:47
Publish the Manuscript Online	2025-02-20 08:38

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Strategies for discovering novel hepatocellular carcinoma biomarkers
Manuscript Source	Unsolicited Manuscript
All Author List	Shi-Tao Wu, Li Zhu, Xiao-Ling Feng, Hao-Yu Wang and Fang Li
ORCID	Author(s) ORCID Number Shi-Tao Wu http://orcid.org/0009-0006-3855-2777 Fang Li http://orcid.org/0000-0002-7061-8514
Funding Agency and Grant Number
Corresponding Author	Fang Li, MD, PhD, Professor, Department of General Surgery, Chongqing General Hospital, No. 118 Xingguang Avenue, Liangjiang New District, Chongqing 401147, China. leef123456@163.com
Key Words	Hepatocellular carcinoma; Biomarkers; Multi-omics; Early detection; Liver cancer
Core Tip	This review provides a comprehensive analysis of current and emerging biomarkers for hepatocellular carcinoma, emphasizing the significance of multi-omics approaches in enhancing diagnostic accuracy and treatment strategies. It highlights the challenges in biomarker discovery, including pre-analytical, analytical, and post-analytical factors, and underscores the need for large-scale validation and cross-disciplinary collaboration. The insights presented aim to advance early detection, improve patient outcomes, and pave the way for personalized treatment approaches in liver cancer management.
Publish Date	2025-02-20 08:38
Citation	<p>Wu ST, Zhu L, Feng XL, Wang HY, Li F. Strategies for discovering novel hepatocellular carcinoma biomarkers. <i>World J Hepatol</i> 2025; 17(2): 101201</p>
URL	https://www.wjgnet.com/1948-5182/full/v17/i2/101201.htm
DOI	https://dx.doi.org/10.4254/wjh.v17.i2.101201

Full Article (PDF)	WJH-17-101201-with-cover.pdf
Manuscript File	101201_Auto_Edited_102145.docx
Answering Reviewers	101201-answering-reviewers.pdf
Audio Core Tip	101201-audio.MP3
Conflict-of-Interest Disclosure Form	101201-conflict-of-interest-statement.pdf
Copyright License Agreement	101201-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	101201-non-native-speakers.pdf
Peer-review Report	101201-peer-reviews.pdf
Scientific Misconduct Check	101201-scientific-misconduct-check.png
Scientific Editor Work List	101201-scientific-editor-work-list.pdf
CrossCheck Report	101201-crosscheck-report.pdf