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9/18/2014 7:49:00 PM | Browse: 497 | Download: 484
Publication Name World Journal of Gastroenterology
Manuscript ID 10127
Country of Manuscript Source China
Received
2014-03-15 14:06
Peer-Review Started
2014-03-17 13:55
To Make the First Decision
2014-04-28 14:08
Return for Revision
2014-05-02 15:21
Revised
2014-05-08 16:35
Second Decision
2014-05-29 20:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-05-29 20:23
Articles in Press
2014-05-29 21:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-06-20 04:49
Typeset the Manuscript
2014-08-25 20:47
Publish the Manuscript Online
2014-09-18 19:50
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Oncology
Manuscript Type Retrospective Study
Article Title Downregulation of miR-193a-5p correlates with lymph node metastasis and poor prognosis in colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Peng Zhang, Deng-Bo Ji, Hai-Bo Han, Yun-Fei Shi, Chang-Zheng Du and Jin Gu
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 30872467
National Natural Science Foundation of China 81030040
National Natural Science Foundation of China 81201965
National Natural Science Foundation of China 81372593
Beijing Natural Science Foundation 7132052
National High-tech R&D Program of China (863 Program) 2012AA02A506
Corresponding author Jin Gu, MD, FACS, Professor, Chairman, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Colorectal Surgery, Peking University Cancer Hospital and Institute, 52 Fucheng Road, Haidian District, Beijing 100142, China. zlgujin@126.com
Keywords miR-193a-5p; Colorectal cancer; Lymph node metastasis; Prognosis; Biomarker
Core Tip We determined the expression of miR-193a-5p in colorectal cancer (CRC) tissues and metastatic lesions in the lymph nodes using quantitative real-time reverse transcriptase polymerase chain reaction. Downregulation of miR-193a-5p correlated with tumor progression, lymph node metastasis and poor survival in CRC patients. These findings suggest that miR-193a-5p could be used as a molecular biomarker of diagnosis, early-stage metastasis prediction, and prognosis forecast for CRC. This is believed to be the first study to investigate the relationship between miR-193a-5p expression and lymph node metastasis in CRC.
Publish Date 2014-09-18 19:50
Citation Zhang P, Ji DB, Han HB, Shi YF, Du CZ, Gu J. Downregulation of miR-193a-5p correlates with lymph node metastasis and poor prognosis in colorectal cancer. World J Gastroenterol 2014; 20(34): 12241-12248
Url http://www.wjgnet.com/1007-9327/full/v20/i34/12241.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i34.12241
Full Article (PDF) WJG-20-12241.pdf
Full Article (Word) WJG-20-12241.doc
Manuscript File 10127-Review.doc
Answering Reviewers 10127-Answering reviewers.pdf
Biostatistics Review Certificate Biostatistician_Review_Report_20140314154747.pdf
Copyright License Agreement 10127-Copyright assignment.pdf
Institutional Review Board Approval Form or Document Ethics_Committee_20140314154710.pdf
Non-Native Speakers of English Editing Certificate 10127-Language certificate.PDF
Peer-review Report 10127-Peer reivew(s).pdf
Scientific Misconduct Check 10127-CrossCheck.jpg
Scientific Editor Work List 10127-Scientific editor work list.pdf