Publication Name	World Journal of Gastroenterology
Manuscript ID	10127
Country	China

Received	2014-03-15 14:06
Peer-Review Started	2014-03-17 13:55
To Make the First Decision	2014-04-28 14:08
Return for Revision	2014-05-02 15:21
Revised	2014-05-08 16:35
Second Decision	2014-05-29 20:12
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-29 20:23
Articles in Press	2014-05-29 21:08
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-06-20 04:49
Typeset the Manuscript	2014-08-25 20:47
Publish the Manuscript Online	2014-09-18 19:50

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Downregulation of miR-193a-5p correlates with lymph node metastasis and poor prognosis in colorectal cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Peng Zhang, Deng-Bo Ji, Hai-Bo Han, Yun-Fei Shi, Chang-Zheng Du and Jin Gu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 30872467 National Natural Science Foundation of China 81030040 National Natural Science Foundation of China 81201965 National Natural Science Foundation of China 81372593 Beijing Natural Science Foundation 7132052 National High-tech R&D Program of China (863 Program) 2012AA02A506
Corresponding Author	Jin Gu, MD, FACS, Professor, Chairman, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Colorectal Surgery, Peking University Cancer Hospital and Institute, 52 Fucheng Road, Haidian District, Beijing 100142, China. zlgujin@126.com
Key Words	miR-193a-5p; Colorectal cancer; Lymph node metastasis; Prognosis; Biomarker
Core Tip	We determined the expression of miR-193a-5p in colorectal cancer (CRC) tissues and metastatic lesions in the lymph nodes using quantitative real-time reverse transcriptase polymerase chain reaction. Downregulation of miR-193a-5p correlated with tumor progression, lymph node metastasis and poor survival in CRC patients. These findings suggest that miR-193a-5p could be used as a molecular biomarker of diagnosis, early-stage metastasis prediction, and prognosis forecast for CRC. This is believed to be the first study to investigate the relationship between miR-193a-5p expression and lymph node metastasis in CRC.
Publish Date	2014-09-18 19:50
Citation	Zhang P, Ji DB, Han HB, Shi YF, Du CZ, Gu J. Downregulation of miR-193a-5p correlates with lymph node metastasis and poor prognosis in colorectal cancer. World J Gastroenterol 2014; 20(34): 12241-12248
URL	http://www.wjgnet.com/1007-9327/full/v20/i34/12241.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i34.12241

Full Article (PDF)	WJG-20-12241.pdf
Full Article (Word)	WJG-20-12241.doc
Manuscript File	10127-Review.doc
Answering Reviewers	10127-Answering reviewers.pdf
Biostatistics Review Certificate	Biostatistician_Review_Report_20140314154747.pdf
Copyright License Agreement	10127-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20140314154710.pdf
Non-Native Speakers of English Editing Certificate	10127-Language certificate.PDF
Peer-review Report	10127-Peer reivew(s).pdf
Scientific Misconduct Check	10127-CrossCheck.jpg
Scientific Editor Work List	10127-Scientific editor work list.pdf