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11/17/2014 3:13:00 PM | Browse: 1001 | Download: 1213
Publication Name World Journal of Gastroenterology
Manuscript ID 10132
Country/Territory China
Received
2014-03-15 13:50
Peer-Review Started
2014-03-15 23:07
To Make the First Decision
2014-05-13 20:23
Return for Revision
2014-05-21 08:53
Revised
2014-06-13 00:00
Second Decision
2014-07-11 17:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-07-11 17:21
Articles in Press
2014-07-11 17:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-07-20 15:52
Typeset the Manuscript
2014-11-01 13:37
Publish the Manuscript Online
2014-11-17 15:12
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biotechnology & Applied Microbiology
Manuscript Type Autobiography
Article Title GW4064, a farnesoid X receptor agonist, upregulates adipokine expression in preadipocytes and HepG2 cells
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Min Xin, Mu-Xiao Zhong, Gong-Li Yang, Yao Peng, Ya-Li Zhang and Wei Zhu
Funding Agency and Grant Number
Funding Agency Grant Number
Guangdong Provincial Science and Technology Projects 2011B050400009
Scientific Research Projects of Hubei Province Education Department B2014055
Corresponding Author Wei Zhu, PhD, Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515, Guangdong Province, China. chnz_w@126.com
Key Words Farnesoid X receptor; Adipokines; Adipokine receptors; 3T3-L1 cells; HepG2 cells; Nonalcoholic fatty liver disease
Core Tip Our study emphasizes for the first time the effect of GW4064, a synthetic farnesoid X receptor (FXR) agonist, on the expression of adipokines and their receptors, and indicates that the way FXR agonist may act in the progress of nonalcoholic fatty liver disease (NAFLD) is at least partially through regulating the expression of adipokines and their receptors. Therefore, our data provide a further theoretical basis for using an FXR agonist in the therapeutic approach of NAFLD.
Publish Date 2014-11-17 15:12
Citation Xin XM, Zhong MX, Yang GL, Peng Y, Zhang YL, Zhu W. GW4064, a farnesoid X receptor agonist, upregulates adipokine expression in preadipocytes and HepG2 cells. World J Gastroenterol 2014; 20(42): 15727-15735
URL http://www.wjgnet.com/1007-9327/full/v20/i42/15727.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i42.15727
Full Article (PDF) WJG-20-15727.pdf
Full Article (Word) WJG-20-15727.doc
Manuscript File 10132-Review.doc
Answering Reviewers 10132-Answering reviewers.pdf
Copyright License Agreement 10132-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 10132-Language Certificate.pdf
Peer-review Report 10132-Peer review.pdf
Scientific Misconduct Check 10132-CrossCheck.jpg
Scientific Editor Work List 10132-Scientific editor work list.pdf