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Articles Published Processes
3/21/2025 6:10:15 AM | Browse: 32 | Download: 30
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Received |
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2024-09-15 02:52 |
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Peer-Review Started |
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2024-09-15 02:52 |
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First Decision by Editorial Office Director |
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2024-09-30 10:41 |
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Return for Revision |
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2024-09-30 10:41 |
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Revised |
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2024-10-15 05:43 |
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Publication Fee Transferred |
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2025-01-16 12:02 |
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Second Decision by Editor |
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2024-12-30 02:28 |
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Second Decision by Editor-in-Chief |
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2025-01-03 07:58 |
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Final Decision by Editorial Office Director |
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2025-01-15 07:24 |
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Articles in Press |
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2025-01-15 07:24 |
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Edit the Manuscript by Language Editor |
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2025-02-22 19:41 |
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Typeset the Manuscript |
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2025-03-13 08:55 |
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Publish the Manuscript Online |
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2025-03-21 06:10 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Basic Study |
| Article Title |
MiR-21-5p-enriched exosomes from hiPSC-derived cardiomyocytes exhibit superior cardiac repair efficacy compared to hiPSC-derived exosomes in a murine MI model
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jing-Jun Jin, Rong-Hua Liu, Jin-Yan Chen, Kun Wang, Jun-Yong Han, Dao-Shun Nie, Yu-Qing Gong, Bin Lin and Guo-Xing Weng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Nonprofit Research Institutes Foundation of Fujian Province, China |
2021R1012005, 2021R1012003 |
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| Corresponding Author |
Jing-Jun Jin, Fujian Key Laboratory of Medical Analysis, Fujian Academy of Medical Sciences, No. 7 Wusi Road, Fuzhou 350001, Fujian Province, China. yolanda_jin19@hotmail.com |
| Key Words |
Human-induced pluripotent stem cell; Human-induced pluripotent stem cell-derived cardiomyocytes; Myocardial infarction; Exosomes; MiR-21-5P; Apoptosis |
| Core Tip |
This study explores human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and their exosomes for myocardial infarction repair. Despite issues with hiPSCs-derived cardiomyocytes, exosomes are promising due to low immunogenicity. By differentiating hiPSCs and characterizing, it’s found they improve cardiac function in a murine myocardial infarction model. HiPSC-derived cardiomyocytes exosomes are superior, with miR-21-5p key. Thus, they may be a strong agent for myocardial repair and inspire further research on exosome treatment for heart disease. |
| Publish Date |
2025-03-21 06:10 |
| Citation |
Jin JJ, Liu RH, Chen JY, Wang K, Han JY, Nie DS, Gong YQ, Lin B, Weng GX. MiR-21-5p-enriched exosomes from hiPSC-derived cardiomyocytes exhibit superior cardiac repair efficacy compared to hiPSC-derived exosomes in a murine MI model. World J Stem Cells 2025; 17(3): 101454 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i3/101454.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i3.101454 |
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