Publication Name	World Journal of Gastroenterology
Manuscript ID	101463
Country	China

Received	2024-09-15 14:14
Peer-Review Started	2024-09-15 14:14
To Make the First Decision
Return for Revision	2024-09-27 19:29
Revised	2024-10-07 15:28
Second Decision	2024-10-30 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-30 14:06
Articles in Press	2024-10-30 14:06
Publication Fee Transferred	2024-10-30 14:29
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-12-04 06:12
Publish the Manuscript Online	2024-12-09 10:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Real-world evidence on the efficacy and safety of vonoprazan-amoxicillin dual therapy for Helicobacter pylori treatment in elderly patients
Manuscript Source	Unsolicited Manuscript
All Author List	Wen Gao, Jing-Wen Li, Hui Ye, Xue-Zhi Zhang, Jian-Xiang Liu and Hong Cheng
ORCID	Author(s) ORCID Number Wen Gao http://orcid.org/0000-0003-3549-6846 Hui Ye http://orcid.org/0000-0001-7607-627X Xue-Zhi Zhang http://orcid.org/0000-0002-4564-7989 Jian-Xiang Liu http://orcid.org/0000-0003-0196-6459 Hong Cheng http://orcid.org/0000-0001-6434-1101
Funding Agency and Grant Number	Funding Agency Grant Number National High Level Hospital Clinical Research Funding (Youth Clinical Research Project of Peking University First Hospital) 2023YC27 Capital’s Funds for Health Improvement and Research 2022-2-40711 National High Level Hospital Clinical Research Funding (Interdepartmental Research Project of Peking University First Hospital) 2024IR20
Corresponding Author	Hong Cheng, MD, Professor, Department of Gastroenterology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China. chenghong1969@163.com
Key Words	Helicobacter pylori; Vonoprazan; Amoxicillin; Dual therapy; Elderly
Core Tip	Vonoprazan-amoxicillin (VA) dual treatment is as effective as traditional bismuth-based quadruple therapy for the eradication of Helicobacter pylori (H. pylori) in the general population. However, the safety of this regimen in the elderly population is unknown. This real-world study retrospectively analyzed data from elderly patients treated for H. pylori infection. VA dual therapy demonstrated good safety and efficacy in the elderly patients with an eradication rate similar to that of the general population. The findings provided evidence supporting the use of VA dual therapy in elderly patients.
Publish Date	2024-12-09 10:39
Citation	<p>Gao W, Li JW, Ye H, Zhang XZ, Liu JX, Cheng H. Real-world evidence on the efficacy and safety of vonoprazan-amoxicillin dual therapy for Helicobacter pylori treatment in elderly patients. <i>World J Gastroenterol</i> 2025; 31(1): 101463</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i1/101463.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i1.101463

Full Article (PDF)	WJG-31-101463-with-cover.pdf
Manuscript File	101463_Auto_Edited_085642.docx
Answering Reviewers	101463-answering-reviewers.pdf
Audio Core Tip	101463-audio.m4a
Biostatistics Review Certificate	101463-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	101463-conflict-of-interest-statement.pdf
Copyright License Agreement	101463-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	101463-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	101463-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	101463-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	101463-non-native-speakers.pdf
Peer-review Report	101463-peer-reviews.pdf
Scientific Misconduct Check	101463-scientific-misconduct-check.png
Scientific Editor Work List	101463-scientific-editor-work-list.pdf
CrossCheck Report	101463-crosscheck-report.png
CrossCheck Report	101463-crosscheck-report.pdf