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Articles Published Processes
3/18/2025 4:25:39 AM | Browse: 47 | Download: 61
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Received |
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2024-09-15 17:18 |
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Peer-Review Started |
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2024-09-15 17:18 |
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To Make the First Decision |
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Return for Revision |
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2025-02-10 09:14 |
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Revised |
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2025-02-17 01:51 |
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Second Decision |
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2025-02-25 02:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-02-25 08:14 |
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Articles in Press |
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2025-02-25 08:14 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-03-17 04:41 |
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Publish the Manuscript Online |
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2025-03-18 04:25 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Evaluation of biological therapies in autoimmune hepatitis: A case-based systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Haifa Eldew and Jonathan Soldera |
| ORCID |
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| Corresponding Author |
Jonathan Soldera, PhD, Professor, Post-Graduation in Acute Medicine and Gastroenterology, University of South Wales, Llantwit Road, Pontypridd, Cardiff CF37 1DL, United Kingdom. jonathansoldera@gmail.com |
| Key Words |
Autoimmune hepatitis; Biological therapies; Belimumab; Rituximab; Basiliximab; Infliximab; Adalimumab |
| Core Tip |
This systematic review highlights the effectiveness of biologic therapies, such as Belimumab and Rituximab, in managing refractory autoimmune hepatitis (AIH) cases. Despite standard treatments with immunomodulators and steroids, some patients remain unresponsive, necessitating alternative options. The review found that Belimumab and Rituximab significantly improved clinical outcomes and liver function in these challenging cases. Additionally, anti-TNF therapies were associated with AIH induction, emphasizing the need for careful monitoring and early detection. These insights advocate for the inclusion of biologics in AIH treatment protocols for patients unresponsive to conventional therapies. |
| Publish Date |
2025-03-18 04:25 |
| Citation |
<p>Eldew H, Soldera J. Evaluation of biological therapies in autoimmune hepatitis: A case-based systematic review. <i>World J Gastrointest Pathophysiol</i> 2025; 16(1): 101481</p> |
| URL |
https://www.wjgnet.com/2150-5330/full/v16/i1/101481.htm |
| DOI |
https://dx.doi.org/10.4291/wjgp.v16.i1.101481 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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