Publication Name	World Journal of Gastroenterology
Manuscript ID	101533
Country	China

Received	2024-09-18 14:46
Peer-Review Started	2024-09-18 14:46
To Make the First Decision
Return for Revision	2024-10-15 03:35
Revised	2024-10-25 09:11
Second Decision	2024-11-04 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-04 06:11
Articles in Press	2024-11-04 06:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-06 00:24
Publish the Manuscript Online	2024-11-12 06:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Editorial
Article Title	Hypoxia-related bioinformatic signatures associated with prognosis and tumor microenvironment of pancreatic cancer: Current status, concerns, and future perspectives
Manuscript Source	Invited Manuscript
All Author List	Dong-Ming Li, Xue-Yuan Cao and Jing Jiang
ORCID	Author(s) ORCID Number Dong-Ming Li http://orcid.org/0000-0002-6492-6668 Xue-Yuan Cao http://orcid.org/0000-0002-1982-1672 Jing Jiang http://orcid.org/0000-0001-9714-9255
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China No.82373664 Scientific and Technological Development program of Jilin Province No.20240402015GH
Corresponding Author	Jing Jiang, MD, PhD, Professor, Department of Clinical Epidemiology, the First Hospital of Jilin University, No. 1 Xinmin Avenue, Chaoyang District, Changchun 130021, Jilin Province, China. jiangjing19702000@jlu.edu.cn
Key Words	Pancreatic cancer; Hypoxia; Bioinformatics analysis; Prognosis; Tumor microenvironment
Core Tip	Currently, hypoxia-related bioinformatic models for pancreatic cancer (PC) primarily evaluate their value for prognosis, tumor microenvironment, and antitumor drug screening. However, these studies did not identify a prognostic model with an optimal predictive performance for PC. Moreover, findings based on bioinformatic analyses may not be completely reliable; thus, more experimental evidence is required. With the integration of multiomics data, the emergence of deep learning, and the application of high-quality experimental programs, the limitations of these models can be overcome and further application in clinical practice may be recommended in the future.
Publish Date	2024-11-12 06:08
Citation	<p>Li DM, Cao XY, Jiang J. Hypoxia-related bioinformatic signatures associated with prognosis and tumor microenvironment of pancreatic cancer: Current status, concerns, and future perspectives. <i>World J Gastroenterol</i> 2024; 30(44): 4689-4696</p>
URL	https://www.wjgnet.com/1007-9327/full/v30/i44/4689.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i44.4689

Full Article (PDF)	WJG-30-4689-with-cover.pdf
Manuscript File	101533_Auto_Edited_012034.docx
Answering Reviewers	101533-answering-reviewers.pdf
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Conflict-of-Interest Disclosure Form	101533-conflict-of-interest-statement.pdf
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Non-Native Speakers of English Editing Certificate	101533-non-native-speakers.pdf
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Scientific Editor Work List	101533-scientific-editor-work-list.pdf
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