Publication Name	World Journal of Diabetes
Manuscript ID	101538
Country	China

Received	2024-09-22 12:48
Peer-Review Started	2024-09-24 03:48
To Make the First Decision
Return for Revision	2024-10-15 07:01
Revised	2024-10-29 06:16
Second Decision	2024-11-13 09:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-26 01:03
Articles in Press	2024-11-26 01:03
Publication Fee Transferred	2024-11-30 13:10
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-12-18 03:38
Publish the Manuscript Online	2024-12-30 09:47

ISSN	1948-9358 (online)
Open Access	Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Basic Study
Article Title	Transcriptome and single-cell profiling of the mechanism of diabetic kidney disease
Manuscript Source	Unsolicited Manuscript
All Author List	Ying Zhou, Xiao Fang, Lin-Jing Huang and Pei-Wen Wu
ORCID	Author(s) ORCID Number Ying Zhou http://orcid.org/0009-0002-9456-1994 Xiao Fang http://orcid.org/0009-0005-8656-8098 Lin-Jing Huang http://orcid.org/0000-0002-0015-251X Pei-Wen Wu http://orcid.org/0000-0003-2748-8854
Funding Agency and Grant Number	Funding Agency Grant Number Joint Funds for the Innovation of Science and Technology, Fujian Province 2021Y9106 Fujian Provincial Health Technology Project 2021GGA033 the Natural Science Foundation of Fujian Province 2024J011234
Corresponding Author	Pei-Wen Wu, Chief Physician, PhD, Professor, Department of Endocrinology, The First Affiliated Hospital of Fujian Medical University, No. 20 Chazhong Road, Fuzhou 350005, Fujian Province, China. wpeiwen@fjmu.edu.cn
Key Words	Diabetic kidney disease; Single-cell RNA sequencing analysis; NOD-like receptor thermal protein domain associated protein 3; Sirtuin 2; Caspase 1
Core Tip	The NOD-like receptor thermal protein domain associated protein 3 inflammasome is implicated in diabetic kidney disease. Our study makes a significant contribution to the literature by identifying sirtuin 2 and caspase 1 as potential biomarkers for diabetic kidney disease, providing new insights into the molecular mechanisms involving the NOD-like receptor thermal protein domain associated protein 3 inflammasome, and suggesting potential targets for diagnosis and treatment, which are crucial for clinical and policy implications.
Publish Date	2024-12-30 09:47
Citation	<p>Zhou Y, Fang X, Huang LJ, Wu PW. Transcriptome and single-cell profiling of the mechanism of diabetic kidney disease. <i>World J Diabetes</i> 2025; 16(2): 101538</p>
URL	https://www.wjgnet.com/1948-9358/full/v16/i2/101538.htm
DOI	https://dx.doi.org/10.4239/wjd.v16.i2.101538

Full Article (PDF)	WJD-16-101538-with-cover.pdf
The ARRIVE Guidelines	101538-The-ARRIVE-Guidelines.pdf
Manuscript File	101538_Auto_Edited_014303.docx
Answering Reviewers	101538-answering-reviewers.pdf
Audio Core Tip	101538-audio.mp3
Biostatistics Review Certificate	101538-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	101538-conflict-of-interest-statement.pdf
Copyright License Agreement	101538-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	101538-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	101538-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate	101538-non-native-speakers.pdf
Supplementary Material	101538-supplementary-material.pdf
Peer-review Report	101538-peer-reviews.pdf
Journal Editor-in-Chief Review Report	101538-journal-editor-in-chief.pdf
Scientific Misconduct Check	101538-scientific-misconduct-check.png
Scientific Editor Work List	101538-scientific-editor-work-list.pdf
CrossCheck Report	101538-crosscheck-report.pdf