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4/16/2025 5:36:38 AM | Browse: 8 | Download: 20
Publication Name World Journal of Experimental Medicine
Manuscript ID 101555
Country United States
Received
2024-09-20 05:40
Peer-Review Started
2024-09-24 03:35
To Make the First Decision
Return for Revision
2025-01-08 12:33
Revised
2025-01-20 20:31
Second Decision
2025-02-05 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-02-06 09:16
Articles in Press
2025-02-06 09:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-02-09 13:24
Publish the Manuscript Online
2025-04-16 05:36
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Toxicology
Manuscript Type Opinion Review
Article Title Biomarkers for tracking metabolic changes pre-post nutritional epigenetics diet/intervention to prevent autism and attention deficit/hyperactivity disorders in children
Manuscript Source Invited Manuscript
All Author List Renee J Dufault
ORCID
Author(s) ORCID Number
Renee J Dufault http://orcid.org/0000-0002-8299-3768
Funding Agency and Grant Number
Corresponding Author Renee J Dufault, PhD, College of Graduate Health Studies, A.T. Still University, 800 W Jefferson Street, Kirksville, MO 63501, United States. rdufault@atsu.edu
Key Words Mercury; Lead; Autism; Attention deficit/hyperactivity disorder; Metallothionein; Nutritional epigenetics; Zinc
Core Tip Increasing evidence supports the nutritional epigenetics model for autism and attention deficit/hyperactivity disorders that explains how unhealthy diet contributes to the epigenetic inheritance of these disorders. An unhealthy diet characterized by excessive intake of ultra-processed foods results in heavy metal exposures and deficits in zinc that may impact metallothionein gene function. Metallothionein gene malfunction may result in the bioaccumulation of mercury and/or lead in the blood depending on diet. Nutritional epigenetics education may be used as an intervention to reduce the intake of ultra-processed foods and heavy metals in expectant mothers and prevent the development of autism and attention deficit/hyperactivity disorders in children.
Publish Date 2025-04-16 05:36
Citation <p>Dufault RJ. Biomarkers for tracking metabolic changes pre-post nutritional epigenetics diet/intervention to prevent autism and attention deficit/hyperactivity disorders in children. <i>World J Exp Med</i> 2025; 15(2): 101555</p>
URL https://www.wjgnet.com/2220-315x/full/v15/i2/101555.htm
DOI https://dx.doi.org/10.5493/wjem.v15.i2.101555
Full Article (PDF) WJEM-15-101555-with-cover.pdf
Manuscript File 101555_Auto_Edited_022352.docx
Answering Reviewers 101555-answering-reviewers.pdf
Audio Core Tip 101555-audio.mp4
Conflict-of-Interest Disclosure Form 101555-conflict-of-interest-statement.pdf
Copyright License Agreement 101555-copyright-assignment.pdf
Peer-review Report 101555-peer-reviews.pdf
Scientific Misconduct Check 101555-scientific-misconduct-check.png
Scientific Editor Work List 101555-scientific-editor-work-list.pdf
CrossCheck Report 101555-crosscheck-report.pdf