Publication Name	World Journal of Gastroenterology
Manuscript ID	101672
Country	China

Received	2024-09-23 02:50
Peer-Review Started	2024-09-23 02:50
To Make the First Decision
Return for Revision	2024-11-22 05:03
Revised	2024-12-03 14:15
Second Decision	2024-12-30 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-30 06:23
Articles in Press	2024-12-30 06:23
Publication Fee Transferred	2024-12-05 10:33
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-01-10 02:50
Publish the Manuscript Online	2025-01-20 07:38

ISSN	1007-9327 (print) and 2219-2840 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	CRAFITY score and nomogram predict the clinical efficacy of lenvatinib combined with immune checkpoint inhibitors in hepatocellular carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Xue Yin, Na Deng, Xiao-Yan Ding, Jing-Long Chen and Wei Sun
ORCID	Author(s) ORCID Number Jing-Long Chen http://orcid.org/0000-0003-1640-7115 Wei Sun http://orcid.org/0000-0001-7511-529X
Funding Agency and Grant Number	Funding Agency Grant Number the Capital’s Funds for Health Improvement and Research SF202222175
Corresponding Author	Wei Sun, MD, Department of Cancer Center, Beijing Ditan Hospital, Capital Medical University, No. 8 Jingshun East Street, Chaoyang District, Beijing 100015, China. sunwei2134@163.com
Key Words	Hepatocellular carcinoma; Lenvatinib; Immune checkpoint inhibitors; C-reactive protein; Alpha-fetoprotein
Core Tip	The CRAFITY score, integrating baseline alpha-fetoprotein and C-reactive protein levels, has been limitedly investigated in patients receiving lenvatinib and programmed cell death protein 1 (PD-1) inhibitors. This study found significant differences in progression-free survival and overall survival across CRAFITY score strata in patients treated with lenvatinib and PD-1 inhibitors. Lower CRAFITY scores were associated with better objective response rates and disease control rates. These findings suggest that the CRAFITY score is a promising predictive tool for treatment response and survival in patients with unresectable hepatocellular carcinoma receiving lenvatinib and PD-1 inhibitors.
Publish Date	2025-01-20 07:38
Citation	<p>Yin X, Deng N, Ding XY, Chen JL, Sun W. CRAFITY score and nomogram predict the clinical efficacy of lenvatinib combined with immune checkpoint inhibitors in hepatocellular carcinoma. <i>World J Gastroenterol</i> 2025; 31(7): 101672</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i7/101672.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i7.101672

Full Article (PDF)	WJG-31-101672-with-cover.pdf
Manuscript File	101672_Auto_Edited_120714.docx
Answering Reviewers	101672-answering-reviewers.pdf
Audio Core Tip	101672-audio.m4a
Biostatistics Review Certificate	101672-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	101672-conflict-of-interest-statement.pdf
Copyright License Agreement	101672-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	101672-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	101672-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	101672-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	101672-non-native-speakers.pdf
Peer-review Report	101672-peer-reviews.pdf
Scientific Misconduct Check	101672-scientific-misconduct-check.png
Scientific Editor Work List	101672-scientific-editor-work-list.pdf
CrossCheck Report	101672-crosscheck-report.pdf