Publication Name	World Journal of Clinical Oncology
Manuscript ID	101686
Country	India

Received	2024-09-23 09:11
Peer-Review Started	2024-09-23 09:11
To Make the First Decision
Return for Revision	2024-10-30 10:04
Revised	2024-11-12 10:05
Second Decision	2024-12-02 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-02 08:47
Articles in Press	2024-12-02 08:47
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-12-08 17:12
Typeset the Manuscript	2025-01-13 01:46
Publish the Manuscript Online	2025-01-21 09:22

ISSN	2218-4333 (online)
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Category	Oncology
Manuscript Type	Editorial
Article Title	Therapeutic potential of kakkatin derivatives against hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Sahiba Chahal and Vikram Patial
ORCID	Author(s) ORCID Number Vikram Patial http://orcid.org/0000-0002-4912-9871
Funding Agency and Grant Number	Funding Agency Grant Number Indian Council of Scientific and Industrial Research No. MLP0204
Corresponding Author	Vikram Patial, Associate Professor, PhD, Dietetics and Nutrition Technology Division, CSIR-Institute of Himalayan Bioresource Technology, No. 6 Post Box, Palampur 176061, Himachal Pradesh, India. vikrampatial@ihbt.res.in
Key Words	Hepatocellular carcinoma; Anti-tumor; Kakkatin; Protooncogenes; Cisplatin
Core Tip	The heterogeneity of tumor cells and their ability to migrate, invade and metastasize distant tissue make diagnosing and developing a cancer treatment difficult. Hepatocellular carcinoma (HCC) is one of the leading causes of cancer deaths, and current therapies are either only effective at the early stage or have side effects. Pueraria flos-based treatment of HCC has shown a better potential to treat HCC than the known chemotherapeutic drug cisplatin. Kakkatin and its derivative 6-(hept-6-yn-1-yloxy)-3-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one, derived from puerariae flos, were used as treatment against HCC and compared with cisplatin.
Publish Date	2025-01-21 09:22
Citation	<p>Chahal S, Patial V. Therapeutic potential of kakkatin derivatives against hepatocellular carcinoma. <i>World J Clin Oncol</i> 2025; 16(3): 101686</p>
URL	https://www.wjgnet.com/2218-4333/full/v16/i3/101686.htm
DOI	https://dx.doi.org/10.5306/wjco.v16.i3.101686

Full Article (PDF)	WJCO-16-101686-with-cover.pdf
Manuscript File	101686_Auto_Edited_083410.docx
Answering Reviewers	101686-answering-reviewers.pdf
Audio Core Tip	101686-audio.mp3
Conflict-of-Interest Disclosure Form	101686-conflict-of-interest-statement.pdf
Copyright License Agreement	101686-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	101686-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	101686-non-native-speakers.pdf
Peer-review Report	101686-peer-reviews.pdf
Scientific Misconduct Check	101686-scientific-misconduct-check.png
Scientific Editor Work List	101686-scientific-editor-work-list.pdf
CrossCheck Report	101686-crosscheck-report.pdf