| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Case Control Study |
| Article Title |
Early detection of gastroparesis with the onset symptom of diabetic ketoacidosis: A retrospective case-control study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li Han, Qing-Yi Peng, Jie Yu, Yi-Wen Liu, Wei Li, Fan Ping, Hua-Bing Zhang, Yu-Xiu Li and Ling-Ling Xu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National High Level Hospital Clinical Research Funding |
2022-PUMCH-B-015 |
| Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences |
2021-I2M-C&T-B-003 |
|
| Corresponding Author |
Ling-Ling Xu, PhD, Professor, Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Translation Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shuaifuyuan Street, Beijing 100730, China. llxuwsh@163.com |
| Key Words |
Diabetes mellitus; Diabetic ketoacidosis; Diabetic gastroparesis; Early detection; Diagnosis |
| Core Tip |
Continuous gastroparesis can repeatedly trigger diabetic ketoacidosis (DKA) and is difficult to correct. We compared the clinical manifestations and biomarkers between DKA and DKA +gastroparesis to promptly detect and diagnose DKA with gastroparesis, relieve gastrointestinal symptoms, and prevent re-induction of DKA. Notably, we found that if patients with DKA present permanent gastrointestinal symptoms without relief, lower HbA1c levels, lower BMI, and higher HDL-C levels after ketone elimination and acidosis correction, gastroparesis should be considered in clinical practice, particularly when the HbA1c level is <8.55%. Furthermore, gastrointestinal examinations should be performed in a timely manner to facilitate diagnosis. |
| Publish Date |
2025-04-18 07:43 |
| Citation |
<p>Han L, Peng QY, Yu J, Liu YW, Li W, Ping F, Zhang HB, Li YX, Xu LL. Early detection of gastroparesis with the onset symptom of diabetic ketoacidosis: A retrospective case-control study. <i>World J Gastroenterol</i> 2025; 31(15): 101695</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i15/101695.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i15.101695 |
