Publication Name	World Journal of Stem Cells
Manuscript ID	101710
Country	China

Received	2024-09-24 05:15
Peer-Review Started	2024-09-24 05:15
To Make the First Decision
Return for Revision	2024-10-17 11:12
Revised	2024-10-17 15:03
Second Decision	2024-12-03 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-03 07:57
Articles in Press	2024-12-03 07:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-12-09 08:20
Publish the Manuscript Online	2024-12-13 03:22

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Interplay and therapeutic implications of colorectal cancer stem cells, tumor microenvironment, and gut microbiota
Manuscript Source	Unsolicited Manuscript
All Author List	Hui Zhang, Bo-Tao Xu, Di-Ping Luo and Tie-Fei He
ORCID	Author(s) ORCID Number Hui Zhang http://orcid.org/0009-0008-5987-6193 Bo-Tao Xu http://orcid.org/0000-0002-4275-0489 Di-Ping Luo http://orcid.org/0009-0009-0029-2035 Tie-Fei He http://orcid.org/0009-0007-4252-6835
Funding Agency and Grant Number
Corresponding Author	Hui Zhang, Department of Emergency Surgery, Zhuji People’s Hospital, No. 9 Jianmin Road, Taozhu Street, Zhuji 311800, Zhejiang Province, China. 13867588467@163.com
Key Words	Colorectal cancer; Stem cells; Tumor microenvironment; Gut microbiota; Treatment resistance; Therapeutic strategies; Personalized medicine; Cancer ecosystem; Research advancements
Core Tip	The core objective of this article is to build upon the compelling arguments presented in the review, highlighting emerging trends, and introducing fresh perspectives to delve deeper into the intricacies of the interplay among these factors. A profound understanding of this interactive relationship is of paramount importance, as it holds the key to unlocking entirely new colorectal cancer treatment strategies and significantly improving patient prognosis.
Publish Date	2024-12-13 03:22
Citation	<p>Zhang H, Xu BT, Luo DP, He TF. Interplay and therapeutic implications of colorectal cancer stem cells, tumor microenvironment, and gut microbiota. <i>World J Stem Cells</i> 2024; 16(12): 1110-1114</p>
URL	https://www.wjgnet.com/1948-0210/full/v16/i12/1110.htm
DOI	https://dx.doi.org/10.4252/wjsc.v16.i12.1110

Full Article (PDF)	WJSC-16-1110-with-cover.pdf
Manuscript File	101710_Auto_Edited_014021.docx
Answering Reviewers	101710-answering-reviewers.pdf
Audio Core Tip	101710-audio.mp3
Conflict-of-Interest Disclosure Form	101710-conflict-of-interest-statement.pdf
Copyright License Agreement	101710-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	101710-non-native-speakers.pdf
Peer-review Report	101710-peer-reviews.pdf
Scientific Misconduct Check	101710-scientific-misconduct-check.png
Scientific Editor Work List	101710-scientific-editor-work-list.pdf
CrossCheck Report	101710-crosscheck-report.pdf