Publication Name	World Journal of Gastroenterology
Manuscript ID	10173
Country	China

Received	2014-03-17 21:39
Peer-Review Started	2014-03-18 08:59
To Make the First Decision	2014-04-15 19:37
Return for Revision	2014-04-23 21:02
Revised	2014-06-23 10:30
Second Decision	2014-07-30 10:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-07-30 10:11
Articles in Press	2014-07-30 10:38
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-08-11 21:42
Typeset the Manuscript	2014-12-04 10:44
Publish the Manuscript Online	2014-12-18 17:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	miR-374b-5p suppresses RECK expression and promotes gastric cancer cell invasion and metastasis
Manuscript Source	Unsolicited Manuscript
All Author List	Juan Xie, Zhi-Hui Tan, Xia Tang, Ming-Shu Mo, Yan-Ping Liu, Run-Liang Gan, Yi Li, Li Zhang and Guo-Qing Li
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81071965
Corresponding Author	Dr. Guo-Qing Li, Department of Gastroenterology, the Second Affiliated Hospital of University of South China, Jiefang Rd 30, Hengyang 421001, Hunan Province, China. ligq1970@163.com
Key Words	Gastric cancer; microRNAs microarray; miR-374b-5p; RECK; Invasion and metastasis
Core Tip	Abnormal expression of microRNAs (miRNAs) is one of the key mechanisms in cancer development, invasion and metastasis. The results of this study identify aberrant expression of 26 miRNAs in two human gastric cancer cell lines, which included upregulation of miR-374b-5p. The invasive and metastatic ability of cancer cells was decreased by transfection of miR-374b-5p antisense oligonucleotides. Furthermore, reversion-inducing cysteine-rich protein with Kazal motif was identified as a target of miR-374b-5p. These data suggest that miR-374b-5p may be a potential biomarker and diagnostic tool for gastric cancer classification and diagnosis.
Publish Date	2014-12-18 17:08
Citation	Xie J, Tan ZH, Tang X, Mo MS, Liu YP, Gan RL, Li Y, Zhang L, Li GQ. miR-374b-5p suppresses RECK expression and promotes gastric cancer cell invasion and metastasis. World J Gastroenterol 2014; 20(46): 17439-17447
URL	http://www.wjgnet.com/1007-9327/full/v20/i46/17439.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i46.17439

Full Article (PDF)	WJG-20-17439.pdf
Full Article (Word)	WJG-20-17439.doc
Manuscript File	10173-Review.docx
Answering Reviewers	10173-Answering reviewers.pdf
Copyright License Agreement	10173-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	10173-Language certificate.pdf
Peer-review Report	10173-Peer review.pdf
Scientific Misconduct Check	10173-CorssCheck.jpg
Scientific Editor Work List	10173-Scientific editor work list.pdf