| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Case Report |
| Article Title |
Genetic disorders leading to severe hyperlipidemia in children: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chun-Xin Jiang, Yu-lin Meng, Dong Chen, Lian-Ping Shi, Guang Yang, Yang Guo, Bo Zhang, Zi-Chen Zhai, Zhi-Jian Wu, Tie-Nan Liu, Zhi-Jun Wang, Xiao Tian and Peng-Yu Su |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Hebei Province |
H2020209160 |
| Scientific Research Projects in Chinese Medicine in Hebei Province |
2019168 |
|
| Corresponding Author |
Peng-Yu Su, Cardiology, North China University of Science and Technology Affiliated Hospital, No.73 South Construction Road, Lubei District, Tangshan 063000, Hebei Province, China. yezi9725@sina.com |
| Key Words |
Hyperlipidemia; Alagille syndrome; Genetic mutation; JAG1; Cholestasis; Low density lipoprotein cholesterol; Traditional Chinese medicine; Case report |
| Core Tip |
The incidence of Alagille syndrome is a rare disease, and no doctor has ever tried traditional Chinese medicine (TCM) in the treatment of Alajeri before, demonstrating the effectiveness of TCM in the treatment of blood lipids. Clinicians need to be careful to ask about the time of onset of the disease when seeing patients, and if they encounter severe hyper lipidaemia they can do genetic testing to rule out inherited metabolic diseases. |
| Publish Date |
2025-02-10 07:51 |
| Citation |
<p>Jiang CX, Meng YL, Chen D, Shi LP, Yang G, Guo Y, Zhang B, Zhai ZC, Wu ZJ, Liu TN, Wang ZJ, Tian X, Su PY. Genetic disorders leading to severe hyperlipidemia in children: A case report. <i>World J Clin Cases</i> 2025; 13(16): 101732</p> |
| URL |
https://www.wjgnet.com/2307-8960/full/v13/i16/101732.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v13.i16.101732 |
