Publication Name	World Journal of Clinical Oncology
Manuscript ID	10182
Country	China

Received	2014-03-19 10:38
Peer-Review Started	2014-03-20 08:03
First Decision by Editorial Office Director
Return for Revision	2014-06-10 08:27
Revised	2014-07-03 17:45
Publication Fee Transferred
Second Decision by Editor	2014-08-31 16:52
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-08-31 17:04
Articles in Press	2014-08-31 17:04
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-10-16 16:00
Publish the Manuscript Online	2014-12-11 14:23

ISSN	2218-4333 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	MiR-210 expression reversed the radioresistance of stem-like cells of oesophageal squamous cell carcinomas
Manuscript Source	Unsolicited Manuscript
All Author List	Xin Chen, Jia Guo, Ru-Xing Xi, Yu-Wei Chang, Fei-Yang Pan and Xiao-Zhi Zhang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 30972962
Corresponding Author	Xiao-Zhi Zhang, MD, Ph D, Chief physician and doctoral tutor.Radiation Department of the First Affiliated Hospital of Medical School of Xi'an Jiaotong University, Xi’an, 710061，Shaanxi Provence, China . E-mail：zhang9149@sina.com
Key Words	MiR-210; Oesophageal squamous-cell carcinoma; Radiation resistance; Cell cycle arrest; Stem-like cells
Core Tip	A low level of miR-210 expression, which is common in oesophageal squamous-cell carcinoma (ESCC) tissues, was found to be negatively correlated with the pathological type and the prognosis of radiotherapy in patients with oesophageal squamous-cell carcinoma, although the sample size was small. A relatively high level of in vitro miR-210 expression reversed the radioresistance of ESCC stem-like cells by decreasing the extents of Ataxia telangiectasia mutated/DNA dependent protein kinase-dependent cell-cycle arrest, failure of DNA double-strand break repair and stem-cell proliferation.
Publish Date	2014-12-11 14:23
Citation	Chen X, Guo J, Xi RX, Chang YW, Pan FY, Zhang XZ. MiR-210 expression reverses radioresistance of stem-like cells of oesophageal squamous cell carcinoma. World J Clin Oncol 2014; 5(5): 1068-1077
URL	http://www.wjgnet.com/2218-4333/full/v5/i5/1068.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i5.1068

Full Article (PDF)	WJCO-5-1068.pdf
Full Article (Word)	WJCO-5-1068.doc
Manuscript File	10182-Review.doc
Answering Reviewers	10182-Answering reviewers.pdf
Copyright License Agreement	10182-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	10182-Language certificate.pdf
Peer-review Report	10182-Peer review(s).pdf
Scientific Misconduct Check	10182-CrossCheck.jpg
Scientific Editor Work List	10182-Scientific editor work list.pdf