Publication Name	World Journal of Clinical Cases
Manuscript ID	101850
Country	Brazil

Received	2024-09-28 13:12
Peer-Review Started	2024-09-28 13:12
To Make the First Decision
Return for Revision	2024-10-22 13:15
Revised	2024-11-04 16:31
Second Decision	2025-03-03 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-04 11:43
Articles in Press	2025-03-04 11:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-03-07 04:27
Publish the Manuscript Online	2025-03-19 06:12

ISSN	2307-8960 (online)
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Category	Respiratory System
Manuscript Type	Retrospective Cohort Study
Article Title	Total adenosine deaminase cases as an inflammatory biomarker of pleural effusion syndrome
Manuscript Source	Unsolicited Manuscript
All Author List	Bernardo Henrique Ferraz Maranhão, Cyro Teixeira da Silva Junior, Jorge Luiz Barillo, Joeber Bernardo Soares Souza, Patricia Siqueira Silva and Roberto Stirbulov
ORCID	Author(s) ORCID Number Bernardo Henrique Ferraz Maranhão http://orcid.org/0000-0002-4793-552X Cyro Teixeira da Silva Junior http://orcid.org/0000-0003-0067-1341 Jorge Luiz Barillo http://orcid.org/0000-0002-6654-4997 Joeber Bernardo Soares Souza http://orcid.org/0000-0002-1494-1050 Patricia Siqueira Silva http://orcid.org/0000-0002-7397-8152 Roberto Stirbulov http://orcid.org/0000-0003-0841-8105
Funding Agency and Grant Number
Corresponding Author	Cyro Teixeira da Silva Junior, Full Professor, MD, PhD, Medical Clinics, Federal Fluminense University, 13 Conceição Avenue, Niteroi City, State of Rio de Janeiro, Niteroi 24020080, Rio de Janeiro, Brazil. ctsilvajunior@predialnet.com.br
Key Words	Pleural effusion; Biomarker; Adenosine deaminase; Inflammation; transudate; Exudate
Core Tip	Non-specialists find it difficult to diagnose pleural effusions. Although diagnosing the syndrome through imaging is simple, determining the cause is more difficult. To treat pleural disease as soon as possible, it is crucial to determine whether it is inflammatory. To our knowledge, this study is the first in Brazil and the world to establish a reference value with strict statistical criteria to classify inflammatory pleural effusion syndrome.
Publish Date	2025-03-19 06:12
Citation	<p>Maranhão BHF, Junior CTDS, Barillo JL, Souza JBS, Silva PS, Stirbulov R. Total adenosine deaminase cases as an inflammatory biomarker of pleural effusion syndrome. <i>World J Clin Cases</i> 2025; 13(19): 101850</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i19/101850.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i19.101850

Full Article (PDF)	WJCC-13-101850-with-cover.pdf
STROBE Statement	101850-STROBE-statement.pdf
Manuscript File	101850_Auto_Edited_032427.docx
Answering Reviewers	101850-answering-reviewers.pdf
Audio Core Tip	101850-audio.mp3
Biostatistics Review Certificate	101850-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	101850-conflict-of-interest-statement.pdf
Copyright License Agreement	101850-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	101850-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	101850-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	101850-non-native-speakers.pdf
Peer-review Report	101850-peer-reviews.pdf
Scientific Misconduct Check	101850-scientific-misconduct-check.png
Scientific Editor Work List	101850-scientific-editor-work-list.pdf
CrossCheck Report	101850-crosscheck-report.pdf