Publication Name	World Journal of Nephrology
Manuscript ID	101861
Country	Chile

Received	2024-09-30 03:44
Peer-Review Started	2024-10-09 01:05
To Make the First Decision
Return for Revision	2024-11-08 04:43
Revised	2024-11-12 22:30
Second Decision	2024-12-02 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-02 08:57
Articles in Press	2024-12-02 08:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-12-16 00:59
Publish the Manuscript Online	2025-01-20 08:27

ISSN	2220-6124 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Urology & Nephrology
Manuscript Type	Editorial
Article Title	Hepatorenal syndrome: Paving a pathway from a fatal condition to an opportunity to preserve kidney function
Manuscript Source	Invited Manuscript
All Author List	Fernando M Gonzalez
ORCID	Author(s) ORCID Number Fernando M Gonzalez http://orcid.org/0000-0003-2742-5220
Funding Agency and Grant Number
Corresponding Author	Fernando M Gonzalez, MD, Department of Nephrology, Faculty of Medicine, Universidad de Chile, Avenida Salvador 486, Providencia, Santiago 7500922, Chile. fgonzalf@uc.cl
Key Words	Hepatorenal syndrome; Acute kidney injury; Oliguria; Ascites; Hibernation; Cirrhosis
Core Tip	Hepatorenal syndrome involves low glomerular filtration rate, hypotension, renin-angiotensin axis activation, decreased water clearance, hyponatremia, and minimal urinary sodium excretion, similar to prerenal acute kidney injury. Notably, liver grafts from these patients can recover function more rapidly than those from other ischemic conditions. Experimental findings suggest potential therapeutic strategies and underscore the need for further research to understand the mechanisms of hepatorenal syndrome and explore possible treatments.
Publish Date	2025-01-20 08:27
Citation	<p>Gonzalez FM. Hepatorenal syndrome: Paving a pathway from a fatal condition to an opportunity to preserve kidney function. <i>World J Nephrol</i> 2025; 14(1): 101861</p>
URL	https://www.wjgnet.com/2220-6124/full/v14/i1/101861.htm
DOI	https://dx.doi.org/10.5527/wjn.v14.i1.101861

Full Article (PDF)	WJN-14-101861-with-cover.pdf
Manuscript File	101861_Auto_Edited_021926.docx
Answering Reviewers	101861-answering-reviewers.pdf
Audio Core Tip	101861-audio.m4a
Conflict-of-Interest Disclosure Form	101861-conflict-of-interest-statement.pdf
Copyright License Agreement	101861-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	101861-non-native-speakers.pdf
Peer-review Report	101861-peer-reviews.pdf
Scientific Misconduct Check	101861-scientific-misconduct-check.png
Scientific Editor Work List	101861-scientific-editor-work-list.pdf
CrossCheck Report	101861-crosscheck-report.pdf